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学科主题: 公共卫生
题名:
Heritability of Smoking, Alcohol Use, and Psychological Characteristics Among Adolescent Twins in Qingdao, China
作者: Unger, Jennifer B.1; Lessov-Schlaggar, Christina N.2; Pang, Zengchang3; Guo, Qian1; Ning, Feng4; Gallaher, Peggy1; Lee, Liming5; Cao, Weihua6; Conti, David6; Johnson, C. Anderson1
关键词: child health ; family medicine ; adolescent health ; public health ; smoking/tobacco/drug abuse ; health informatics ; health management ; health education ; health promotion ; medical statistics
刊名: ASIA-PACIFIC JOURNAL OF PUBLIC HEALTH
发表日期: 2011-07-01
DOI: 10.1177/1010539509351052
卷: 23, 期:4, 页:568-580
收录类别: SCI ; SSCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Public, Environmental & Occupational Health
研究领域[WOS]: Public, Environmental & Occupational Health
关键词[WOS]: ENVIRONMENTAL-INFLUENCES ; SUBSTANCE USE ; NICOTINE DEPENDENCE ; CIGARETTE-SMOKING ; YOUNG ADULTHOOD ; TOBACCO USE ; INITIATION ; REGISTRY ; ANXIETY ; SAMPLE
英文摘要:

Background: Previous studies of genetic and environmental influences on adolescent substance use have been limited to Western samples. Methods:This study assesses genetic and environmental contributions to cigarette smoking, alcohol use, and psychological variables (depression, anxiety, aggression, hostility) among 602 pairs of adolescent twins, 11 to 19 years old, in Qingdao, China. Results: Heritable influences were more pronounced for alcohol use than cigarette smoking. In univariate analyses, no heritable effects were found for depression or aggression, and modest heritability was found for anxiety. Hostility was relatively more heritable in girls than boys. Bivariate associations between substance use and psychological measures could be attributed to a combination of common genetic and environmental factors. Conclusions: Among Chinese adolescents, experimentation with tobacco is familial, and experimentation with alcohol is heritable. The genetic and environmental architecture of hostility differs by gender. Consistency of univariate results with Western adolescent samples appears limited to the alcohol use measures.

语种: 英语
所属项目编号: 5P50CA084735
项目资助者: NIH Transdisciplinary Tobacco Use Research Center
WOS记录号: WOS:000293149200012
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/52242
Appears in Collections:北京大学公共卫生学院_期刊论文

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作者单位: 1.Univ So Calif, Los Angeles, CA USA
2.Claremont Grad Univ, San Dimas, CA 91773 USA
3.Qingdao Municipal Ctr Dis Control & Prevent, Qingdao, Peoples R China
4.Washington Univ, Sch Med St Louis, St Louis, MO 63130 USA
5.Chinese Acad Med Sci, Peking Union Med Coll, Beijing 100730, Peoples R China
6.Peking Univ, Sch Publ Hlth, Hlth Sci Ctr, Beijing 100871, Peoples R China

Recommended Citation:
Unger, Jennifer B.,Lessov-Schlaggar, Christina N.,Pang, Zengchang,et al. Heritability of Smoking, Alcohol Use, and Psychological Characteristics Among Adolescent Twins in Qingdao, China[J]. ASIA-PACIFIC JOURNAL OF PUBLIC HEALTH,2011,23(4):568-580.
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