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Associations between DSM-IV mental disorders and onset of self-reported peptic ulcer in the World Mental Health Surveys
Scott, Kate M.1; Alonso, Jordi2,3,4; de Jonge, Peter5; Carmen Viana, Maria6; Liu, Zhaorui7; O&prime1; Neill, Siobhan8; Aguilar-Gaxiola, Sergio9; Bruffaerts, Ronny10; Caldas-de-Almeida, Jose Miguel11,12; Stein, Dan J.13; Angermeyer, Matthias14; Benjet, Corina15; de Girolamo, Giovanni16; Firuleasa, Ingrid-Laura17; Hu, Chiyi18,19; Kiejna, Andrzej20; Kovess-Masfety, Viviane21; Levinson, Daphna22; Nakane, Yoshibumi23; Piazza, Marina24; Posada-Villa, Jose A.25; Khalaf, Mohammad Salih1; Lim, Carmen C. W.1; Kessler, Ronald C.1
关键词Mental Disorders Depression Anxiety Alcohol Abuse And Dependence Peptic Ulcer
刊名JOURNAL OF PSYCHOSOMATIC RESEARCH
2013-08-01
DOI10.1016/j.jpsychores.2013.04.007
75期:2页:121-127
收录类别SCI ; SSCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Psychiatry
资助者Health Research Council of New Zealand ; Health Research Council of New Zealand
研究领域[WOS]Psychiatry
关键词[WOS]CHILDHOOD PHYSICAL ABUSE ; POSTTRAUMATIC-STRESS-DISORDER ; HELICOBACTER-PYLORI ; PSYCHIATRIC-DISORDERS ; SOCIAL-CONSEQUENCES ; MAJOR DEPRESSION ; UNITED-STATES ; DISEASE ; ADULTS ; ANXIETY
英文摘要

Objective: Recent research demonstrating concurrent associations between mental disorders and peptic ulcers has renewed interest in links between psychological factors and ulcers. However, little is known about associations between temporally prior mental disorders and subsequent ulcer onset. Nor has the potentially confounding role of childhood adversities been explored. The objective of this study was to examine associations between a wide range of temporally prior DSM-IV mental disorders and subsequent onset of ulcer, without and with adjustment for mental disorder comorbidity and childhood adversities.

Methods: Face-to-face household surveys conducted in 19 countries (n = 52,095; person years = 2,096,486). The Composite International Diagnostic Interview retrospectively assessed lifetime prevalence and age at onset of 16 DSM-IV mental disorders. Peptic ulcer onset was assessed in the same interview by self-report of physician′s diagnosis and year of diagnosis. Survival analyses estimated associations between first onset of mental disorders and subsequent ulcer onset.

Results: After comorbidity and sociodemographic adjustment, depression, social phobia, specific phobia, post-traumatic stress disorder, intermittent explosive disorder, alcohol and drug abuse disorders were significantly associated with ulcer onset (ORs 1.3-1.6). Increasing number of lifetime mental disorders was associated with ulcer onset in a dose-response fashion. These associations were only slightly attenuated by adjustment for childhood adversities.

Conclusions: A wide range of mental disorders were linked with the self-report of subsequent peptic ulcer onset These associations require confirmation in prospective designs, but are suggestive of a role for mental disorders in contributing to ulcer vulnerability, possibly through abnormalities in the physiological stress response associated with mental disorders. (C) 2013 Elsevier Inc. All rights reserved.

语种英语
资助者Health Research Council of New Zealand ; Health Research Council of New Zealand
WOS记录号WOS:000323397100004
Citation statistics
Cited Times:8[WOS]   [WOS Record]     [Related Records in WOS]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/52254
Collection北京大学精神卫生研究所
作者单位1.Univ Otago, Dept Psychol Med, Dunedin, New Zealand
2.Mental Hlth Serv Minist Hlth, Jerusalem, Israel
3.IMIM Hosp Mar Med Res Inst, Barcelona, Spain
4.Pompeu Fabra Univ, Barcelona, Spain
5.CIBERESP, Barcelona, Spain
6.Peking Univ, Inst Mental Hlth, Beijing 100871, Peoples R China
7.Univ Peruana Cayetano Heredia, Lima, Peru
8.Univ Colegio Mayor Cundinamarca, Bogota, Colombia
9.Univ Ulster, Psychol Res Inst, Londonderry, England
10.Katholieke Univ Leuven, Univ Psychiat Centrum, Louvain, Belgium
11.Univ Cape Town, Dept Psychiat, Cape Town, South Africa
12.Ctr Publ Mental Hlth, Gosing Am Wagram, Austria
13.IRCCS Ctr S Giovanni Dio Fatebenefratelli, Brescia, Italy
14.Natl Sch Publ Hlth Management & Profess Dev, Bucharest, Romania
15.Shenzhin Inst Mental Hlth, Shenzhin, Guangdong, Peoples R China
16.Shenzhen Kangning Hosp, Shenzhen, Guangdong, Peoples R China
17.Wroclaw Med Univ, Dept & Clin Psychiat, Wroclaw, Poland
18.Univ Groningen, Univ Med Ctr Groningen, NL-9713 AV Groningen, Netherlands
19.Univ Fed Espirito Santo, Dept Social Med, Vitoria, Brazil
20.Univ Calif Davis, Sch Med, CRHD, Community Engagement Program,CTSC, Sacramento, CA 95817 USA
21.Univ Nova Lisboa, Fac Ciencias Med, Chron Dis Res Ctr CEDOC, P-1200 Lisbon, Portugal
22.Univ Nova Lisboa, Fac Ciencias Med, Dept Mental Hlth, P-1200 Lisbon, Portugal
23.Natl Inst Psychiat Ramon Fuente, Mexico City, DF, Mexico
24.Paris Descartes Univ Res Unit EHESP Sch Publ Hlth, Dept Epidemiol & Biostat, Paris, France
25.Nagasaki Int Univ, Fac Human Sociol, Dept Social Work, Nagasaka, Yamanashi, Japan
26.Harvard Univ, Sch Med, Dept Hlth Care Policy, Boston, MA 02115 USA
Recommended Citation
GB/T 7714
Scott, Kate M.,Alonso, Jordi,de Jonge, Peter,et al. Associations between DSM-IV mental disorders and onset of self-reported peptic ulcer in the World Mental Health Surveys[J]. JOURNAL OF PSYCHOSOMATIC RESEARCH,2013,75(2):121-127.
APA Scott, Kate M..,Alonso, Jordi.,de Jonge, Peter.,Carmen Viana, Maria.,Liu, Zhaorui.,...&Kessler, Ronald C..(2013).Associations between DSM-IV mental disorders and onset of self-reported peptic ulcer in the World Mental Health Surveys.JOURNAL OF PSYCHOSOMATIC RESEARCH,75(2),121-127.
MLA Scott, Kate M.,et al."Associations between DSM-IV mental disorders and onset of self-reported peptic ulcer in the World Mental Health Surveys".JOURNAL OF PSYCHOSOMATIC RESEARCH 75.2(2013):121-127.
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