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学科主题: 公共卫生
题名:
Effects of lutein and zeaxanthin on aspects of eye health
作者: Ma, Le; Lin, Xiao-Ming
关键词: lutein, zeaxanthin ; carotenoid, macular pigment ; age-related macular degeneration ; cataract
刊名: JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
发表日期: 2010-01-15
DOI: 10.1002/jsfa.3785
卷: 90, 期:1, 页:2-12
收录类别: SCI
文章类型: Review
WOS标题词: Science & Technology
类目[WOS]: Agriculture, Multidisciplinary ; Chemistry, Applied ; Food Science & Technology
研究领域[WOS]: Agriculture ; Chemistry ; Food Science & Technology
关键词[WOS]: AGE-RELATED MACULOPATHY ; NUTRITION EXAMINATION SURVEY ; ABSORBING INTRAOCULAR-LENS ; RETINAL-PIGMENT EPITHELIUM ; 3RD NATIONAL-HEALTH ; BEAVER DAM EYE ; MACULAR DEGENERATION ; RETINITIS-PIGMENTOSA ; PRIMATE RETINAS ; PROTECTIVE ROLE
英文摘要:

Lutein and zeaxanthin are members of the oxygenated carotenoids found particularly in egg yolks and dark-green leafy vegetables. A great deal of research has focused on their beneficial roles in eye health. The present article summarises the current literature related to the bioactivity of these carotenoids, emphasising their effects and possible mechanisms of action in relation to human eye health. Available evidence demonstrates that lutein and zeaxanthin are widely distributed in a number of body tissues and are uniquely concentrated in the retina and lens, indicating that each has a possible specific function in these two vital ocular tissues. Most of epidemiological studies and clinical trials support the notion that lutein and zeaxanthin have a potential role in the prevention and treatment of certain eye diseases such as age-related macular degeneration, cataract and retinitis pigmentosa. The biological mechanisms for the protective effects of these carotenoids may include powerful blue-light filtering activities and antioxidant properties. Although most studies point towards significant health benefits from lutein and zeaxanthin, further large-scale randomised supplementation trials are needed to define their effects on ocular function in health and disease. (c) 2009 Society of Chemical Industry

语种: 英语
所属项目编号: NSFC-30671758 ; 06094
项目资助者: National Natural Science Foundation of China ; Chinese Nutrition Society
WOS记录号: WOS:000272561000002
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/52300
Appears in Collections:北京大学公共卫生学院_期刊论文

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作者单位: Peking Univ, Sch Publ Hlth, Dept Food Hyg & Nutr, Beijing 100191, Peoples R China

Recommended Citation:
Ma, Le,Lin, Xiao-Ming. Effects of lutein and zeaxanthin on aspects of eye health[J]. JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE,2010,90(1):2-12.
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