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学科主题临床医学
RHINO-ORBITAL-CEREBRAL MYCOSIS AND CAVERNOUS THROMBOSIS
Li, D. M.1,2,3; Shang, P. P.1,2; Zhu, L.4; De Hoog, G. S.3
关键词Rhinocerebral Orbit Alternaria Infectoria Cavernous Sinus Thrombosis Mycosis Mucormycosis Zygomycosis
刊名EUROPEAN JOURNAL OF INFLAMMATION
2014
12期:1页:1-10
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Immunology
研究领域[WOS]Immunology
关键词[WOS]OF-THE-LITERATURE ; RHINOCEREBRAL MUCORMYCOSIS ; ORBITOCEREBRAL MUCORMYCOSIS ; INVASIVE ASPERGILLOSIS ; MYCOTIC-ANEURYSM ; SINUS-THROMBOSIS ; BASILAR ARTERY ; CAROTID-ARTERY ; OPTIC-NERVE ; ZYGOMYCOSIS
英文摘要

Rhino-orbital-cerebral mycosis (ROCM) is a life-threatening fungal disease associated mostly with Mucoralean fungi. The infection presents as headache, vision loss, proptosis, ptosis, painful ophthalmoplegia, and peripheral face palsy, with a high mortality (>80% for infections that spread to the brain) and severe morbidity, such as eyeball exenteration and vision loss. In our hospital, a 61-year-old woman with diabetes was diagnosed with rhino-orbital-cerebral infection caused by Allternaria infectoria. Cavernous sinus thromboses (CST) were seen in surgery, pathology, and MIRE. She did not respond to potent antifungal therapy until the adding of anti-thrombosis drugs. By analyzing our case, together with the ones that have been published, we realized that fungal thrombosis in the cavernous sinus is the main pathophysiological problem in ROCM that typically shows mass enhancement within the cavernous sinus in radiographic images, thrombosis with characteristics of ischemia and infarction in pathology. Anticoagulation/antithrombus therapy might be helpful in the management of ROCM if potent antifungal treatment does not have effect.

语种英语
WOS记录号WOS:000334651900001
引用统计
被引频次:1[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/52349
专题北京大学第三临床医学院_皮肤科
作者单位1.Peking Univ, Hosp 3, Mycol Lab, Beijing 100191, Peoples R China
2.Cent Bur Schimmelcultures, Utrecht, Netherlands
3.Peking Univ, Hosp 3, Dept Dermatol, Beijing 100191, Peoples R China
4.Peking Univ, Hosp 3, Dept Otorhinolaryngol, Beijing 100191, Peoples R China
推荐引用方式
GB/T 7714
Li, D. M.,Shang, P. P.,Zhu, L.,et al. RHINO-ORBITAL-CEREBRAL MYCOSIS AND CAVERNOUS THROMBOSIS[J]. EUROPEAN JOURNAL OF INFLAMMATION,2014,12(1):1-10.
APA Li, D. M.,Shang, P. P.,Zhu, L.,&De Hoog, G. S..(2014).RHINO-ORBITAL-CEREBRAL MYCOSIS AND CAVERNOUS THROMBOSIS.EUROPEAN JOURNAL OF INFLAMMATION,12(1),1-10.
MLA Li, D. M.,et al."RHINO-ORBITAL-CEREBRAL MYCOSIS AND CAVERNOUS THROMBOSIS".EUROPEAN JOURNAL OF INFLAMMATION 12.1(2014):1-10.
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