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IR@PKUHSC  > 北京大学口腔医学院  > 口腔修复科  > 期刊论文
学科主题: 口腔医学
题名:
Molecular and Cellular Regulatory Mechanisms of Tongue Myogenesis
作者: Parada, C.1; Han, D.1,2; Chai, Y.1
关键词: craniofacial biology/genetics ; developmental biology ; muscle biology myoblasts ; neural crest ; tongue
刊名: JOURNAL OF DENTAL RESEARCH
发表日期: 2012-06-01
DOI: 10.1177/0022034511434055
卷: 91, 期:6, 页:528-535
收录类别: SCI
文章类型: Review
WOS标题词: Science & Technology
类目[WOS]: Dentistry, Oral Surgery & Medicine
研究领域[WOS]: Dentistry, Oral Surgery & Medicine
关键词[WOS]: NEURAL CREST CELLS ; MUSCLE PROGENITOR CELLS ; C-MET RECEPTOR ; SATELLITE CELLS ; SKELETAL-MUSCLE ; PRECURSOR CELLS ; CRANIOFACIAL MUSCLES ; TENDON FIBROBLASTS ; GENE ; EXPRESSION
英文摘要:

The tongue exerts crucial functions in our daily life. However, we know very little about the regulatory mechanisms of mammalian tongue development. In this review, we summarize recent findings of the molecular and cellular mechanisms that control tissue-tissue interactions during tongue morphogenesis. Specifically, cranial neural crest cells (CNCC) lead the initiation of tongue bud formation and contribute to the interstitial connective tissue, which ultimately compartmentalizes tongue muscles and serves as their attachments. Occipital somite-derived cells migrate into the tongue primordium and give rise to muscle cells in the tongue. The intimate relationship between CNCC-and mesoderm-derived cells, as well as growth and transcription factors that have been shown to be crucial for tongue myogenesis, clearly indicate that tissue-tissue interactions play an important role in regulating tongue morphogenesis.

语种: 英语
所属项目编号: DE014078 ; DE012711 ; DE017007
项目资助者: National Institute of Dental and Craniofacial Research, NIH
WOS记录号: WOS:000303809000002
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/52370
Appears in Collections:北京大学口腔医学院_口腔修复科_期刊论文

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作者单位: 1.Univ So Calif, Ctr Craniofacial Mol Biol, Los Angeles, CA 90033 USA
2.Peking Univ, Dept Prosthodont, Sch & Hosp Stomatol, Beijing 100871, Peoples R China

Recommended Citation:
Parada, C.,Han, D.,Chai, Y.. Molecular and Cellular Regulatory Mechanisms of Tongue Myogenesis[J]. JOURNAL OF DENTAL RESEARCH,2012,91(6):528-535.
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