北京大学医学部机构知识库
Advanced  
IR@PKUHSC  > 北京大学第三临床医学院  > 肿瘤放疗科  > 期刊论文
学科主题: 临床医学
题名:
A Novel Conformal Arc Technique for Postoperative Whole Pelvic Radiotherapy for Endometrial Cancer
作者: Yan, Ruijie; Jiang, Weijuan; Wang, Junjie
关键词: Endometrial cancer ; Conformal arc therapy ; Whole pelvic radiotherapy ; Intensity-modulated radiation therapy ; 3-Dimensional conformal radiotherapy
刊名: INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER
发表日期: 2009-12-01
DOI: 10.1111/IGC.0b013e3181bd35a6
卷: 19, 期:9, 页:1574-1579
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Oncology ; Obstetrics & Gynecology
研究领域[WOS]: Oncology ; Obstetrics & Gynecology
关键词[WOS]: INTENSITY-MODULATED RADIOTHERAPY ; ACUTE HEMATOLOGIC TOXICITY ; RADIATION-THERAPY ; GYNECOLOGIC MALIGNANCIES ; ADJUVANT TREATMENT ; CERVICAL-CANCER ; CARCINOMA ; SURGERY ; TRIAL ; RISK
英文摘要:

Introduction: Conventional whole pelvic radiotherapy (WPRT) with 3-dimensional conformal radiotherapy (3D-CRT) exposes most of the contents of the true pelvis to the prescribed dose. Intensity-modulated radiation therapy (IMRT) provides more conformal dose distribution and better sparing of critical structures for WPRT. However, IMRT is more complicated in planning and delivery, requiring more expensive equipment and time-consuming quality assurance. We explore and evaluate a novel conformal arc radio-therapeutic technique for postoperative WPRT for endometrial cancer in this study.

Methods: This technique involves 2-axis conformal arc therapy (2A-CAT) with 180-degree rotation around 2 isocenters each in 2 separate dose-shaping structures. Dosimetric comparison with 3D-CRT and IMRT for 10 endometrial cancer patients undergoing postoperative WPRT was performed to evaluate this new 2A-CAT technique.

Results: The mean conformity indices were 0.83, 0.61, and 0.88 for 2A-CAT, 3D-CRT, and IMRT, respectively. The mean homogeneity indices were 1.15, 1.08, and 1.10. The mean doses to bowel, rectum, bladder, and pelvic bone marrow were, respectively, 1.19, 3.39, 4.65, and 1.64 Gy lower with 2A-CAT than with 3D-CRT (P < 0.05), whereas a little higher than with IMRT The mean dose to normal tissue was 1.87 Gy higher with 2A-CAT than with IMRT (P = 0.00).

Conclusions: In postoperative WPRT for endometrial cancer, 2A-CAT significantly improves the dose conformity and sparing of bowel, rectum, and bladder compared with 3D-CRT. Despite dose uniformity and conformity being still inferior to those of IMRT, its simplicity and extensive availability combined with further improvement warrant it as a potential shortcut alternative to IMRT.

语种: 英语
WOS记录号: WOS:000272898400022
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/52373
Appears in Collections:北京大学第三临床医学院_肿瘤放疗科_期刊论文

Files in This Item:

There are no files associated with this item.


作者单位: Peking Univ, Ctr Canc, Hosp 3, Dept Radiat Oncol, Beijing 100191, Peoples R China

Recommended Citation:
Yan, Ruijie,Jiang, Weijuan,Wang, Junjie. A Novel Conformal Arc Technique for Postoperative Whole Pelvic Radiotherapy for Endometrial Cancer[J]. INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER,2009,19(9):1574-1579.
Service
Recommend this item
Sava as my favorate item
Show this item's statistics
Export Endnote File
Google Scholar
Similar articles in Google Scholar
[Yan, Ruijie]'s Articles
[Jiang, Weijuan]'s Articles
[Wang, Junjie]'s Articles
CSDL cross search
Similar articles in CSDL Cross Search
[Yan, Ruijie]‘s Articles
[Jiang, Weijuan]‘s Articles
[Wang, Junjie]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit
所有评论 (0)
暂无评论
 
评注功能仅针对注册用户开放,请您登录
您对该条目有什么异议,请填写以下表单,管理员会尽快联系您。
内 容:
Email:  *
单位:
验证码:   刷新
您在IR的使用过程中有什么好的想法或者建议可以反馈给我们。
标 题:
 *
内 容:
Email:  *
验证码:   刷新

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Copyright © 2007-2017  北京大学医学部 - Feedback
Powered by CSpace