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学科主题: 精神卫生
题名:
Associations between DSM-IV mental disorders and subsequent heart disease onset: Beyond depression
作者: Scott, Kate M.1; de Jonge, Peter2; Alonso, Jordi3; Viana, Maria Carmen4; Liu, Zhaorui5; O&prime1; Neill, Siobhan6; Aguilar-Gaxiola, Sergio7; Bruffaerts, Ronny8; Caldas-de-Almeida, Jose Miguel9,10; Stein, Dan J.11; de Girolamo, Giovanni12; Florescu, Silvia E.1; Hu, Chiyi13,14; Taib, Nezar Ismet15; Lepine, Jean-Pierre16; Levinson, Daphna17; Matschinger, Herbert18; Elena Medina-Mora, Maria19; Piazza, Marina20; Posada-Villa, Jose A.21; Uda, Hidenori1; Wojtyniak, Bogdan J.22; Lim, Carmen C. W.1; Kessler, Ronald C.23
关键词: Depression ; Anxiety disorders ; Alcohol abuse ; Heart disease ; Comorbidity
刊名: INTERNATIONAL JOURNAL OF CARDIOLOGY
发表日期: 2013-10-15
DOI: 10.1016/j.ijcard.2013.08.012
卷: 168, 期:6, 页:5293-5299
收录类别: SCI ; SSCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Cardiac & Cardiovascular Systems
研究领域[WOS]: Cardiovascular System & Cardiology
关键词[WOS]: GENERALIZED ANXIETY DISORDER ; CARDIOVASCULAR-DISEASE ; RATE-VARIABILITY ; PANIC DISORDER ; HEALTH SURVEYS ; RISK-FACTORS ; FOLLOW-UP ; SYMPTOMS ; EVENTS ; ANTIDEPRESSANTS
英文摘要:

Background: Prior studies on the depression-heart disease association have not usually used diagnosticmeasures of depression, or taken other mental disorders into consideration. As a result, it is not clear whether the association between depression and heart disease onset reflects a specific association, or the comorbidity between depression and other mental disorders. Additionally, the relative magnitude of associations of a range of mental disorders with heart disease onset is unknown.

Methods: Face-to-face household surveys were conducted in 19 countries (n = 52,095; person years = 2,141,194). The Composite International Diagnostic Interview retrospectively assessed lifetime prevalence and age at onset of 16 DSM-IV mental disorders. Heart disease was indicated by self-report of physician′s diagnosis, or self-report of heart attack, togetherwith their timing (year). Survival analyses estimated associations between first onset of mental disorders and subsequent heart disease onset.

Results: After comorbidity adjustment, depression, panic disorder, specific phobia, post-traumatic stress disorder and alcohol use disorders were associated with heart disease onset (ORs 1.3-1.6). Increasing number of mental disorderswas associated with heart disease in a dose-response fashion. Mood disorders and alcohol abusewere more strongly associated with earlier onset than later onset heart disease. Associations did not vary by gender.

Conclusions: Depression, anxiety and alcohol use disorders were significantly associated with heart disease onset; depression was the weakest predictor. If confirmed in future prospective studies, the breadth of psychopathology′s links with heart disease onset has substantial clinical and public health implications. (C) 2013 Elsevier Ireland Ltd. All rights reserved.

语种: 英语
所属项目编号: R01 MH070884 ; R13-MH066849 ; R01-MH069864 ; R01 DA016558 ; FIRCA R03-TW006481
项目资助者: National Institute ofMental Health (NIMH) ; Catherine T. MacArthur Foundation ; Pfizer Foundation ; US Public Health Service ; Fogarty International Center ; Pan American Health Organization
WOS记录号: WOS:000326220300036
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/52389
Appears in Collections:北京大学精神卫生研究所_期刊论文

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作者单位: 1.Univ Otago, Dept Psychol Med, Dunedin, New Zealand
2.Univ Groningen, Univ Med Ctr Groningen, NL-9713 AV Groningen, Netherlands
3.CIBER Epidemiol & Salud Publ CIBERESP, Barcelona, Catalonia, Spain
4.Fed Univ Espirito Santo UFES, Dept Social Med, Vitoria, Espirito Santo, Spain
5.Peking Univ, Inst Mental Hlth, Beijing 100871, Peoples R China
6.Univ Ulster, Sch Psychol, Coleraine BT52 1SA, Londonderry, North Ireland
7.Univ Calif Davis, Ctr Reducing Hlth Dispar, Sch Med, Sacramento, CA 95817 USA
8.Univ Hosp Gasthuisberg, B-3000 Louvain, Belgium
9.Univ Nova Lisboa, Fac Ciencias Med, Chron Dis Res Ctr CEDOC, P-1200 Lisbon, Portugal
10.Univ Nova Lisboa, Fac Ciencias Med, Dept Mental Hlth, P-1200 Lisbon, Portugal
11.Univ Cape Town, Dept Psychiat & Mental Hlth, ZA-7925 Cape Town, South Africa
12.IRCCS Ctr S Giovanni Dio Fatebenefratelli, Inst Municipal Invest Med IMIM Hosp Mar, Hlth Serv Res Unit, Bologna, Italy
13.Shenzhen Inst Mental Hlth, Shenzhen, Peoples R China
14.Shenzhen Kangning Hosp, Shenzhen, Peoples R China
15.Mental Hlth Ctr Duhok, Kurdistan Region, Iraq
16.Hop Lariboisiere Fernand Widal, Paris, France
17.Minist Hlth, Mental Hlth Serv, Jerusalem, Israel
18.Univ Leipzig, Psychiat Clin, D-04109 Leipzig, Germany
19.Natl Inst Psychiat, Mexico City, DF, Mexico
20.Inst Colombiano Sistema Nervioso, Bogota, DC, Colombia
21.Harvard Univ, Sch Med, Dept Healthcare Policy, Boston, MA USA
22.Univ Peruana Cayetano Heredia, Fac Salud Publ & Adm FASPA, Lima, Peru
23.Natl Inst Publ Hlth Natl Inst Hyg, Dept Ctr Monitoring & Anal Populat Hlth, Warsaw, Poland

Recommended Citation:
Scott, Kate M.,de Jonge, Peter,Alonso, Jordi,et al. Associations between DSM-IV mental disorders and subsequent heart disease onset: Beyond depression[J]. INTERNATIONAL JOURNAL OF CARDIOLOGY,2013,168(6):5293-5299.
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