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学科主题: 药学
题名:
Reagent-free synthesis of 2,3,4-polysubstituted tetrahydroquinolines: application to the formal synthesis of (+/-)-martinellic acid and martinelline
作者: Rong, Zhouting; Li, Qingjiang; Lin, Wenhan; Jia, Yanxing
关键词: Tetrahydroquinoline ; Reagent-free ; Martinellic acid ; Formal synthesis
刊名: TETRAHEDRON LETTERS
发表日期: 2013-08-14
DOI: 10.1016/j.tetlet.2013.06.028
卷: 54, 期:33, 页:4432-4434
收录类别: SCI ; IC ; CCR
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Chemistry, Organic
研究领域[WOS]: Chemistry
关键词[WOS]: SOLID SUPPORT SYNTHESIS ; CYCLIZATION-ELIMINATION REACTION ; 3 COMPONENT CONDENSATION ; (-)-MARTINELLIC ACID ; POVAROV REACTION ; POLYSUBSTITUTED TETRAHYDROQUINOLINES ; ENANTIOSELECTIVE SYNTHESIS ; AROMATIC-AMINES ; ALDEHYDES ; 1,2,3,4-TETRAHYDROQUINOLINES
英文摘要:

The simple and one-pot method for the synthesis of polysubstituted tetrahydroquinolines from readily available anilines and aldehydes under reagent-free conditions has been developed. The scope of the transformation has been demonstrated. This method has been successfully applied to the rapid formal synthesis of (+/-)-martinellic acid and martinelline. (C) 2013 The Authors. Published by Elsevier Ltd. All rights reserved.

语种: 英语
所属项目编号: 21290180 ; 20972007 ; 2010CB833200 ; 20120001110100
项目资助者: National Natural Science Foundation of China ; National Basic Research Program of China (973 Program) ; Ph.D. Programs Foundation of Ministry of Education of China
WOS记录号: WOS:000322287300020
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/52456
Appears in Collections:北京大学药学院_期刊论文

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作者单位: Peking Univ, Sch Pharmaceut Sci, State Key Lab Nat & Biomimet Drugs, Beijing 100191, Peoples R China

Recommended Citation:
Rong, Zhouting,Li, Qingjiang,Lin, Wenhan,et al. Reagent-free synthesis of 2,3,4-polysubstituted tetrahydroquinolines: application to the formal synthesis of (+/-)-martinellic acid and martinelline[J]. TETRAHEDRON LETTERS,2013,54(33):4432-4434.
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