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学科主题: 精神卫生
题名:
Demographic and clinical differences between early- and late-onset major depressions in thirteen psychiatric institutions in China
作者: Hu, Chen1; Geng, Ying1; Feng, Yuan1; Wang, Gang1; Ungvari, Gabor S.2; Chiu, Helen F. K.3; Kilbourne, Amy M.4,5; Lai, Kelly Y. C.3; Si, Tian-Mei6,7; Zheng, Qi-Wen8; Fang, Yi-Ru9; Lu, Zheng10; Yang, Hai-Chen11; Hu, Jian12; Chen, Zhi-Yu13; Huang, Yi14; Sun, Jing15; Wang, Xiao-Ping16; Li, Hui-Chun17; Zhang, Jin-Bei18; Xiang, Yu-Tao19
关键词: Early onset ; Major depressive disorder ; Prescription patterns
刊名: JOURNAL OF AFFECTIVE DISORDERS
发表日期: 2015
DOI: 10.1016/j.jdad.2014.09.008
卷: 170, 页:266-269
收录类别: SCI ; SSCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Clinical Neurology ; Psychiatry
研究领域[WOS]: Neurosciences & Neurology ; Psychiatry
关键词[WOS]: MOOD DISORDER QUESTIONNAIRE ; BIPOLAR SPECTRUM DISORDER ; VALIDATION ; VARIABLES ; BURNOUT ; HEALTH ; SLEEP
英文摘要:

Background: Little is known about the demographic and clinical differences between early-and late- onset depressions (EOD and LOD, respectively) in Chinese patients. This study examined the demographic and clinical profile of EOD (< =25 years) compared to LOD (> 25 years) in China.

Methods: A consecutively recruited sample of 1178 patients with MDD was assessed in 13 psychiatric hospitals or psychiatric units of general hospitals in China nationwide. The cross-sectional data of patients′ demographic and clinical characteristics and prescriptions of psychotropic drugs including antidepressants, mood stabilizers, antipsychotics and benzodiazepines were recorded using a standardized protocol and data collection procedure.

Results: Two hundred and seventy five (23.3%) of the 1178 patients fulfilled criteria for EOD. In multiple logistic regression analyses, compared to LOD patients their EOD counterparts were more likely to be unmarried and unemployed, had more atypical and psychotic depressive episodes, had bipolar features, while they had more lifetime depressive episodes.

Conclusions: The demographic and more severe clinical features of EOD in Chinese patients were basically consistent with those found in Western populations. The association between socio-cultural factors and development of EOD warrants further studies. (C) 2014 Elsevier B.V. All rights reserved.

语种: 英语
所属项目编号: 2007BAl17B05
项目资助者: Ministry of Science and Technology of China
WOS记录号: WOS:000344226700039
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/52546
Appears in Collections:北京大学精神卫生研究所_期刊论文

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作者单位: 1.Peking Univ, Inst Mental Hlth, Beijing 100871, Peoples R China
2.Hangzhou Seventh Peoples Hosp, Hangzhou, Zhejiang, Peoples R China
3.Univ Macau, Fac Hlth Sci, Macao, Peoples R China
4.Vet Adm Ann Arbor Ctr Clin Management Res, Ann Arbor, MI USA
5.Minist Mental Hlth, Key Lab Mental Hlth, Beijing, Peoples R China
6.Capital Med Univ, Beijing Anding Hosp, Mood Disorders Ctr, Beijing, Peoples R China
7.Univ Notre Dame, Australia Marian Ctr, Perth, WA, Australia
8.Chinese Univ Hong Kong, Dept Psychiat, Hong Kong, Hong Kong, Peoples R China
9.Univ Michigan, Sch Med, Dept Psychiat, Ann Arbor, MI 48109 USA
10.Peking Univ, Hlth Sci Ctr, Dept Epidemiol & Biostat, Beijing 100871, Peoples R China
11.Shanghai Jiao Tong Univ, Sch Med, Shanghai Mental Hlth Ctr, Div Mood Disorders, Shanghai 200030, Peoples R China
12.Tongji Univ, Sch Med, Shanghai Tongji Hosp, Shanghai 200092, Peoples R China
13.Shenzhen Mental Hlth Ctr, Div Mood Disorders, Shenzhen, Guangdong, Peoples R China
14.Harbin Med Univ, Hosp 1, Harbin, Heilongjiang Pr, Peoples R China
15.Sichuan Univ, West China Hosp, Chengdu, Sichuan Provinc, Peoples R China
16.Nanjing Med Univ, Affiliated Brain Hosp, Nanjing, Jiangsu, Peoples R China
17.Cent S Univ, Xiangya Hosp 2, Mental Hlth Inst, Changsha, Hunan, Peoples R China
18.Zhejiang Univ, Coll Med, Affiliated Hosp 2, Hangzhou 310003, Zhejiang, Peoples R China
19.Sun Yat Sen Univ, Affiliated Hosp 3, Guangzhou 510275, Guangdong, Peoples R China

Recommended Citation:
Hu, Chen,Geng, Ying,Feng, Yuan,et al. Demographic and clinical differences between early- and late-onset major depressions in thirteen psychiatric institutions in China[J]. JOURNAL OF AFFECTIVE DISORDERS,2015,170:266-269.
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