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Demographic and clinical differences between early- and late-onset major depressions in thirteen psychiatric institutions in China
Hu, Chen1; Geng, Ying1; Feng, Yuan1; Wang, Gang1; Ungvari, Gabor S.2; Chiu, Helen F. K.3; Kilbourne, Amy M.4,5; Lai, Kelly Y. C.3; Si, Tian-Mei6,7; Zheng, Qi-Wen8; Fang, Yi-Ru9; Lu, Zheng10; Yang, Hai-Chen11; Hu, Jian12; Chen, Zhi-Yu13; Huang, Yi14; Sun, Jing15; Wang, Xiao-Ping16; Li, Hui-Chun17; Zhang, Jin-Bei18; Xiang, Yu-Tao19
关键词Early Onset Major Depressive Disorder Prescription Patterns
刊名JOURNAL OF AFFECTIVE DISORDERS
2015
DOI10.1016/j.jdad.2014.09.008
170页:266-269
收录类别SCI ; SSCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Clinical Neurology ; Psychiatry
研究领域[WOS]Neurosciences & Neurology ; Psychiatry
关键词[WOS]MOOD DISORDER QUESTIONNAIRE ; BIPOLAR SPECTRUM DISORDER ; VALIDATION ; VARIABLES ; BURNOUT ; HEALTH ; SLEEP
英文摘要

Background: Little is known about the demographic and clinical differences between early-and late- onset depressions (EOD and LOD, respectively) in Chinese patients. This study examined the demographic and clinical profile of EOD (< =25 years) compared to LOD (> 25 years) in China.

Methods: A consecutively recruited sample of 1178 patients with MDD was assessed in 13 psychiatric hospitals or psychiatric units of general hospitals in China nationwide. The cross-sectional data of patients′ demographic and clinical characteristics and prescriptions of psychotropic drugs including antidepressants, mood stabilizers, antipsychotics and benzodiazepines were recorded using a standardized protocol and data collection procedure.

Results: Two hundred and seventy five (23.3%) of the 1178 patients fulfilled criteria for EOD. In multiple logistic regression analyses, compared to LOD patients their EOD counterparts were more likely to be unmarried and unemployed, had more atypical and psychotic depressive episodes, had bipolar features, while they had more lifetime depressive episodes.

Conclusions: The demographic and more severe clinical features of EOD in Chinese patients were basically consistent with those found in Western populations. The association between socio-cultural factors and development of EOD warrants further studies. (C) 2014 Elsevier B.V. All rights reserved.

语种英语
WOS记录号WOS:000344226700039
项目编号2007BAl17B05
资助机构Ministry of Science and Technology of China
引用统计
被引频次:2[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/52546
专题北京大学精神卫生研究所
作者单位1.Peking Univ, Inst Mental Hlth, Beijing 100871, Peoples R China
2.Hangzhou Seventh Peoples Hosp, Hangzhou, Zhejiang, Peoples R China
3.Univ Macau, Fac Hlth Sci, Macao, Peoples R China
4.Vet Adm Ann Arbor Ctr Clin Management Res, Ann Arbor, MI USA
5.Minist Mental Hlth, Key Lab Mental Hlth, Beijing, Peoples R China
6.Capital Med Univ, Beijing Anding Hosp, Mood Disorders Ctr, Beijing, Peoples R China
7.Univ Notre Dame, Australia Marian Ctr, Perth, WA, Australia
8.Chinese Univ Hong Kong, Dept Psychiat, Hong Kong, Hong Kong, Peoples R China
9.Univ Michigan, Sch Med, Dept Psychiat, Ann Arbor, MI 48109 USA
10.Peking Univ, Hlth Sci Ctr, Dept Epidemiol & Biostat, Beijing 100871, Peoples R China
11.Shanghai Jiao Tong Univ, Sch Med, Shanghai Mental Hlth Ctr, Div Mood Disorders, Shanghai 200030, Peoples R China
12.Tongji Univ, Sch Med, Shanghai Tongji Hosp, Shanghai 200092, Peoples R China
13.Shenzhen Mental Hlth Ctr, Div Mood Disorders, Shenzhen, Guangdong, Peoples R China
14.Harbin Med Univ, Hosp 1, Harbin, Heilongjiang Pr, Peoples R China
15.Sichuan Univ, West China Hosp, Chengdu, Sichuan Provinc, Peoples R China
16.Nanjing Med Univ, Affiliated Brain Hosp, Nanjing, Jiangsu, Peoples R China
17.Cent S Univ, Xiangya Hosp 2, Mental Hlth Inst, Changsha, Hunan, Peoples R China
18.Zhejiang Univ, Coll Med, Affiliated Hosp 2, Hangzhou 310003, Zhejiang, Peoples R China
19.Sun Yat Sen Univ, Affiliated Hosp 3, Guangzhou 510275, Guangdong, Peoples R China
推荐引用方式
GB/T 7714
Hu, Chen,Geng, Ying,Feng, Yuan,et al. Demographic and clinical differences between early- and late-onset major depressions in thirteen psychiatric institutions in China[J]. JOURNAL OF AFFECTIVE DISORDERS,2015,170:266-269.
APA Hu, Chen.,Geng, Ying.,Feng, Yuan.,Wang, Gang.,Ungvari, Gabor S..,...&Xiang, Yu-Tao.(2015).Demographic and clinical differences between early- and late-onset major depressions in thirteen psychiatric institutions in China.JOURNAL OF AFFECTIVE DISORDERS,170,266-269.
MLA Hu, Chen,et al."Demographic and clinical differences between early- and late-onset major depressions in thirteen psychiatric institutions in China".JOURNAL OF AFFECTIVE DISORDERS 170(2015):266-269.
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