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Six insecticidal isoryanodane diterpenoids from the bark and twigs of Itoa orientalis
Chai, Xing-Yun; Bai, Chang-Cai; Shi, Hai-Ming; Xu, Zheng-Ren; Ren, Hong-Yan; Li, Fei-Fei; Lu, Ya-Nan; Song, Yue-Lin; Tu, Peng-Fei
关键词Itols A-d Isoryanodane Glycosides Itoa Orientalis X-ray Diffraction Insecticidal Activity
刊名TETRAHEDRON
2008-06-09
DOI10.1016/j.tet.2008.04.022
64期:24页:5743-5747
收录类别SCI ; IC
文章类型Article
WOS标题词Science & Technology
类目[WOS]Chemistry, Organic
研究领域[WOS]Chemistry
关键词[WOS]PHENOLIC GLYCOSIDES
英文摘要

Four rare isoryanodane diterpenoids namely itols A-D (1-4) and two isoryanosdane glucosides (5 and 6) were isolated from the bark and twigs of Itoa orientalis. Their structures were determined by NMR and MS techniques and the Structure of 1 was confirmed by a single-crystal X-ray diffraction. These six diterpenoids obviously showed insecticidal activity against Spodoptera exigua, with LC(50) 28.62 ppm for 1 and 52.76 ppm for 2, respectively. In anti-inflammatory assay, compounds 1 and 4-6 showed anti-COX-2 activity, with inhibitory rates of 54.7-78.3% at 10 mu m. (C) 2008 Elsevier Ltd. All rights reserved.

语种英语
WOS记录号WOS:000256335800016
引用统计
被引频次:6[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/52603
专题北京大学药学院_天然药物学系
作者单位Peking Univ, Hlth Sci Ctr, Sch Pharmaceut Sci, Dept Nat Med, Beijing 100083, Peoples R China
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Chai, Xing-Yun,Bai, Chang-Cai,Shi, Hai-Ming,et al. Six insecticidal isoryanodane diterpenoids from the bark and twigs of Itoa orientalis[J]. TETRAHEDRON,2008,64(24):5743-5747.
APA Chai, Xing-Yun.,Bai, Chang-Cai.,Shi, Hai-Ming.,Xu, Zheng-Ren.,Ren, Hong-Yan.,...&Tu, Peng-Fei.(2008).Six insecticidal isoryanodane diterpenoids from the bark and twigs of Itoa orientalis.TETRAHEDRON,64(24),5743-5747.
MLA Chai, Xing-Yun,et al."Six insecticidal isoryanodane diterpenoids from the bark and twigs of Itoa orientalis".TETRAHEDRON 64.24(2008):5743-5747.
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