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IR@PKUHSC  > 北京大学第二临床医学院  > 胃肠外科  > 期刊论文
学科主题: 临床医学
题名:
Clinical and microbiological features of community-acquired and nosocomial bloodstream infections in the surgical department of a tertiary-care hospital in Beijing
作者: Lu You1,3; Guo Peng1; Ye Ying-jiang1; Wang Hui2; Shen Zhan-long1; Wang Qi2; Zhao Chun-jiang2; Gao Zhi-dong1; Zhang Xin1; Cao Jian1; Jiang Ke-wei1; Wang Shan1
关键词: bacteremia ; bloodstream infection ; surgery ; nosocomial infection ; community-acquired infection
刊名: CHINESE MEDICAL JOURNAL
发表日期: 2013-11-20
DOI: 10.3760/cma.j.issn.0366-6999.20131302
卷: 126, 期:22, 页:4242-4246
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Medicine, General & Internal
研究领域[WOS]: General & Internal Medicine
关键词[WOS]: RISK-FACTORS ; INTENSIVE-CARE ; RESISTANCE ; EPIDEMIOLOGY ; SURVEILLANCE ; MORTALITY ; BACTERIA
英文摘要:

Background Bloodstream infections (BSIs) remain a major cause of morbidity and mortality in patients undergoing surgery. This study aimed at elucidating the clinical characteristics of community-acquired BSIs (CABs) and nosocomial BSIs (nBSIs) in patients admitted to the surgical wards of a teaching hospital in Beijing, China.

Methods This cross-sectional study compared 191 episodes of BSIs in 4074 patients admitted to the surgical wards between January 2008 and December 2011. Cases of BSIs were classified as CABs or nBSIs, and the characteristics, relevant treatments, and outcomes of CABs and nBSIs were compared.

Results Of the 191 BSIs, 52 (27.2%) and 139 (72.8%) were CABs and nBSIs, respectively. Escherichia coli, coagulase-negative staphylococci, and Klebsiella spp, were the most frequently isolated microorganisms. There were significant differences between CABs and nBSIs with respect to the use of hormonal drugs, ventilation, acute physiology and chronic health evaluation (APACHE) II and American Society of Anesthesiologists scores, and prevalence of cancer (P <0.05). Empirical antibacterial therapy did not decrease the crude mortality, but multivariate analysis showed that high APACHE II was independently associated with a risk of mortality (odds ratio =0.97, 95% confidence interval: 0.93-1.02 for APACHE II).

Conclusions We found significant differences in the clinical characteristics of surgical patients with CABs and nBSIs. The outcome of patients seems to be related to high APACHE II scores.

语种: 英语
所属项目编号: 2012EP00102 ; 20110001120086 ; RDC2011-14 ; RDU2011-06
项目资助者: National Science and Technology Support Plan ; Higher School Specialized Research Fund for the Doctoral Program of the New Teacher Class ; Development and Research Fund of Peking University People&prime ; s Hospital ; Fund of Peking-Tsinghua Center for Life Sciences
WOS记录号: WOS:000327916600009
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/52609
Appears in Collections:北京大学第二临床医学院_胃肠外科_期刊论文

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作者单位: 1.Peking Univ, Peking Univ Peoples Hosp, Dept Surg Gastroenterol, Beijing 100044, Peoples R China
2.Peking Univ, Peking Univ Peoples Hosp, Dept Clin Lab, Beijing 100044, Peoples R China
3.Shihezi Univ, Affiliated Hosp 1, Dept Hepatobiliary Surg, Shihezi 832008, Xinjiang, Peoples R China

Recommended Citation:
Lu You,Guo Peng,Ye Ying-jiang,et al. Clinical and microbiological features of community-acquired and nosocomial bloodstream infections in the surgical department of a tertiary-care hospital in Beijing[J]. CHINESE MEDICAL JOURNAL,2013,126(22):4242-4246.
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