IR@PKUHSC  > 北京大学第二临床医学院  > 胃肠外科
学科主题临床医学
Clinical and microbiological features of community-acquired and nosocomial bloodstream infections in the surgical department of a tertiary-care hospital in Beijing
Lu You1,3; Guo Peng1; Ye Ying-jiang1; Wang Hui2; Shen Zhan-long1; Wang Qi2; Zhao Chun-jiang2; Gao Zhi-dong1; Zhang Xin1; Cao Jian1; Jiang Ke-wei1; Wang Shan1
关键词Bacteremia Bloodstream Infection Surgery Nosocomial Infection Community-acquired Infection
刊名CHINESE MEDICAL JOURNAL
2013-11-20
DOI10.3760/cma.j.issn.0366-6999.20131302
126期:22页:4242-4246
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Medicine, General & Internal
研究领域[WOS]General & Internal Medicine
关键词[WOS]RISK-FACTORS ; INTENSIVE-CARE ; RESISTANCE ; EPIDEMIOLOGY ; SURVEILLANCE ; MORTALITY ; BACTERIA
英文摘要

Background Bloodstream infections (BSIs) remain a major cause of morbidity and mortality in patients undergoing surgery. This study aimed at elucidating the clinical characteristics of community-acquired BSIs (CABs) and nosocomial BSIs (nBSIs) in patients admitted to the surgical wards of a teaching hospital in Beijing, China.

Methods This cross-sectional study compared 191 episodes of BSIs in 4074 patients admitted to the surgical wards between January 2008 and December 2011. Cases of BSIs were classified as CABs or nBSIs, and the characteristics, relevant treatments, and outcomes of CABs and nBSIs were compared.

Results Of the 191 BSIs, 52 (27.2%) and 139 (72.8%) were CABs and nBSIs, respectively. Escherichia coli, coagulase-negative staphylococci, and Klebsiella spp, were the most frequently isolated microorganisms. There were significant differences between CABs and nBSIs with respect to the use of hormonal drugs, ventilation, acute physiology and chronic health evaluation (APACHE) II and American Society of Anesthesiologists scores, and prevalence of cancer (P <0.05). Empirical antibacterial therapy did not decrease the crude mortality, but multivariate analysis showed that high APACHE II was independently associated with a risk of mortality (odds ratio =0.97, 95% confidence interval: 0.93-1.02 for APACHE II).

Conclusions We found significant differences in the clinical characteristics of surgical patients with CABs and nBSIs. The outcome of patients seems to be related to high APACHE II scores.

语种英语
WOS记录号WOS:000327916600009
项目编号2012EP00102 ; 20110001120086 ; RDC2011-14 ; RDU2011-06
资助机构National Science and Technology Support Plan ; Higher School Specialized Research Fund for the Doctoral Program of the New Teacher Class ; Development and Research Fund of Peking University People&prime ; s Hospital ; Fund of Peking-Tsinghua Center for Life Sciences
引用统计
被引频次:2[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/52609
专题北京大学第二临床医学院_胃肠外科
作者单位1.Peking Univ, Peking Univ Peoples Hosp, Dept Surg Gastroenterol, Beijing 100044, Peoples R China
2.Peking Univ, Peking Univ Peoples Hosp, Dept Clin Lab, Beijing 100044, Peoples R China
3.Shihezi Univ, Affiliated Hosp 1, Dept Hepatobiliary Surg, Shihezi 832008, Xinjiang, Peoples R China
推荐引用方式
GB/T 7714
Lu You,Guo Peng,Ye Ying-jiang,et al. Clinical and microbiological features of community-acquired and nosocomial bloodstream infections in the surgical department of a tertiary-care hospital in Beijing[J]. CHINESE MEDICAL JOURNAL,2013,126(22):4242-4246.
APA Lu You.,Guo Peng.,Ye Ying-jiang.,Wang Hui.,Shen Zhan-long.,...&Wang Shan.(2013).Clinical and microbiological features of community-acquired and nosocomial bloodstream infections in the surgical department of a tertiary-care hospital in Beijing.CHINESE MEDICAL JOURNAL,126(22),4242-4246.
MLA Lu You,et al."Clinical and microbiological features of community-acquired and nosocomial bloodstream infections in the surgical department of a tertiary-care hospital in Beijing".CHINESE MEDICAL JOURNAL 126.22(2013):4242-4246.
条目包含的文件
条目无相关文件。
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Lu You]的文章
[Guo Peng]的文章
[Ye Ying-jiang]的文章
百度学术
百度学术中相似的文章
[Lu You]的文章
[Guo Peng]的文章
[Ye Ying-jiang]的文章
必应学术
必应学术中相似的文章
[Lu You]的文章
[Guo Peng]的文章
[Ye Ying-jiang]的文章
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。