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学科主题: 精神卫生
题名:
Tobacco use and dementia: evidence from the 1066 dementia population-based surveys in Latin America, China and India
作者: Ferri, Cleusa P.1; West, Robert2; Moriyama, Tais S.1,3; Acosta, Daisy4; Guerra, Mariella1,5; Huang, Yueqin6; Jacob, K. S.7; Ribeiro, Wagner1,3,8; Llibre de Rodriguez, Juan J.1; Salas, Aquiles9; Luisa Sosa, Ana1,10; Williams, Joseph11; Acosta, Isaac10; Liu, Zhaouri6; Guerra Hernandez, Milagros A.12; Prince, Martin J.1
关键词: dementia ; Alzheimer&prime ; s disease ; vascular dementia ; tobacco ; developing countries
刊名: INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY
发表日期: 2011-11-01
DOI: 10.1002/gps.2661
卷: 26, 期:11, 页:1177-1185
收录类别: SCI ; SSCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Geriatrics & Gerontology ; Gerontology ; Psychiatry
研究领域[WOS]: Geriatrics & Gerontology ; Psychiatry
关键词[WOS]: MALE BRITISH DOCTORS ; ALZHEIMERS-DISEASE ; CIGARETTE-SMOKING ; RISK-FACTORS ; DIAGNOSIS ; HEALTH ; COHORT ; METAANALYSIS ; ALGORITHM ; COUNTRIES
英文摘要:

Objectives: To assess the association between tobacco consumption and dementia using the same methodology in seven developing countries, testing the specific hypotheses that higher exposure to tobacco is associated with a higher prevalence of dementia, that the association is limited to smoked tobacco and is stronger for vascular dementia compared to Alzheimer′s disease.

Methods: Cross-sectional surveys conducted on individuals aged 65+. A total of 15 022 residents in specified catchment areas were assessed face-to-face using a standardised protocol, which included dementia diagnosis and detailed information on past and current tobacco consumption, and on important potential confounders of this association.

Results: A high proportion of participants were never smokers (52% in Dominican Republic to 83% in Peru), most of those who ever used tobacco in China and India were still smoking at age 65 and above (80% and 84%, respectively). There was a positive association between history of tobacco smoke exposure (pack years up to age 50) and dementia (pooled PR = 1.003; 95% CI 1.001-1.005), Alzheimer′s disease (pooled PR = 1.007; 95% CI, 1.003-1.011) and Vascular Dementia (pooled PR = 1.003; 95% CI = 1.001-1.005). These associations were attenuated but remained significant if exposure after the age of 50 was included. In India there was no association between smokeless tobacco and dementia.

Conclusions: Dementia in developing countries appears to be positively associated with history of tobacco smoking but not smokeless tobacco use. Selective quitting in later life may bias estimation of associations. Copyright (C) 2011 John Wiley & Sons, Ltd.

语种: 英语
项目资助者: WellcomeTrust ; Rock-efeller Foundation ; World Health Organisation (India) ; World Health Organisation (Dominican Republic) ; World Health Organisation (China) ; US Alzheimer&prime ; s Association (Peru) ; US Alzheimer&prime ; s Association (Mexico) ; US Alzheimer&prime ; s Association (Argentina) ; FONACIT/CDCH/UCV (Venezuela)
WOS记录号: WOS:000296447300010
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/52697
Appears in Collections:北京大学精神卫生研究所_期刊论文

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作者单位: 1.Kings Coll London, Inst Psychiat, Hlth Serv & Populat Res Dept, London WC2R 2LS, England
2.UCL, Dept Epidemiol & Publ Hlth, Canc Res UK Hlth Behav Res Ctr, London, England
3.Univ Fed Sao Paulo, Dept Psychiat, Sao Paulo, Brazil
4.Univ Nacl Pedro Henriquez Urena, Santo Domingo, Dominican Rep
5.Univ Peruana Cayetano Heredia, Lima, Peru
6.Peking Univ, Inst Mental Hlth, Beijing 100871, Peoples R China
7.Christian Med Coll & Hosp, Vellore, Tamil Nadu, India
8.Med Univ Havana, Havana, Cuba
9.Caracas Univ Hosp, Caracas, Venezuela
10.Natl Inst Neurol & Neurosurg Mexico, Mexico City, DF, Mexico
11.VHS, Community Hlth Serv, Madras, Tamil Nadu, India
12.Policlin Univ 27 Noviembre, Fac Med Finlay Albarran, Havana, Cuba

Recommended Citation:
Ferri, Cleusa P.,West, Robert,Moriyama, Tais S.,et al. Tobacco use and dementia: evidence from the 1066 dementia population-based surveys in Latin America, China and India[J]. INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY,2011,26(11):1177-1185.
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