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Alterations of nitrate and nitrite content in saliva, serum, and urine in patients with salivary dysfunction
Xia, DS1; Deng, DJ1; Wang, SL1
关键词Nitrate Nitrite Saliva Sialosis Sjogren&Prime s Syndrome
刊名JOURNAL OF ORAL PATHOLOGY & MEDICINE
2003-02-01
32期:2页:95-99
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Dentistry, Oral Surgery & Medicine ; Pathology
研究领域[WOS]Dentistry, Oral Surgery & Medicine ; Pathology
关键词[WOS]DIETARY NITRATE ; SJOGRENS-SYNDROME ; OXIDE ; CIRCULATION ; INGESTION ; CANCER
英文摘要

Background: The role of the salivary glands in the maintenance of nitrate and nitrite in saliva is poorly understood. The aim was to study alterations of nitrate and nitrite metabolisms in patients with Sjogren′s syndrome (SS) or sialosis.

Methods: Saliva, serum, and urine samples were collected from healthy volunteers (n = 29), patients with SS (n = 31), and patients with sialosis (n = 30). Concentrations of nitrate and nitrite were determined by high-performance liquid chromatography (HPLC).

Results: In the healthy group, the highest concentration of nitrate was found in parotid saliva (172 mg/l), followed by urine (160 mg/l), whole saliva (97 mg/l), and serum (33 mg/l). In the SS group, concentration of nitrate was decreased in parotid saliva and whole saliva, and increased significantly in urine. Concentration of nitrite in whole saliva was significantly decreased in the SS group and increased in the sialosis group.

Conclusion: Hypofunction of the salivary glands is associated with significant changes of nitrate and nitrite levels in the saliva and urine.

语种英语
WOS记录号WOS:000180606800006
引用统计
被引频次:18[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/52726
专题北京大学临床肿瘤学院
北京大学第三临床医学院_医院感染管理科
北京大学临床肿瘤学院_病因学研究室
作者单位1.Peking Univ, Sch Oncol, Beijing 100034, Peoples R China
2.Beijing Inst Canc Res, Beijing 100034, Peoples R China
3.Capital Univ Med Sci, Fac Stomatol, Salivary Gland Dis Ctr, Beijing 100050, Peoples R China
推荐引用方式
GB/T 7714
Xia, DS,Deng, DJ,Wang, SL. Alterations of nitrate and nitrite content in saliva, serum, and urine in patients with salivary dysfunction[J]. JOURNAL OF ORAL PATHOLOGY & MEDICINE,2003,32(2):95-99.
APA Xia, DS,Deng, DJ,&Wang, SL.(2003).Alterations of nitrate and nitrite content in saliva, serum, and urine in patients with salivary dysfunction.JOURNAL OF ORAL PATHOLOGY & MEDICINE,32(2),95-99.
MLA Xia, DS,et al."Alterations of nitrate and nitrite content in saliva, serum, and urine in patients with salivary dysfunction".JOURNAL OF ORAL PATHOLOGY & MEDICINE 32.2(2003):95-99.
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