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IR@PKUHSC  > 北京大学第三临床医学院  > 皮肤科  > 期刊论文
学科主题: 临床医学
题名:
Identification and quantification of major peanut allergens (in China) with IgE-binding property
作者: Cong, Yan-Jun1; Lou, Fei1; Li, Lin-Feng2; Xue, Wen-Tong1; Wang, Jing2; Zhang, Hui1; Fan, Jun-Feng1
刊名: JOURNAL OF FOOD BIOCHEMISTRY
发表日期: 2008-06-01
卷: 32, 期:3, 页:353-367
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Biochemistry & Molecular Biology ; Food Science & Technology
研究领域[WOS]: Biochemistry & Molecular Biology ; Food Science & Technology
关键词[WOS]: ARA-H-I ; ATOPIC-DERMATITIS ; PROTEINS ; ARA-H-1 ; HYPERSENSITIVITY ; EPITOPES ; SERA
英文摘要:

Peanut allergens have not been studied in China. This study aimed to investigate (1) whether there are differences in the relative amounts of major peanut allergens between the Chinese peanut varieties and the American, and (2) the effect of cooking methods on peanut allergenicity. The allergenic property of raw peanuts and peanut preparations was assessed by immunoblotting and enzyme-linked immunosorbent assay. The relative contents of the major peanut allergens were quantified by sodium dodecyl sulphate-polyacrylamide gel electrophoresis densitometry. For results, Ara h 1 and Ara h 3 were major peanut allergens in China. The amounts of Ara h 1 and Ara h 3 in peanut varieties differ significantly and were both lower than the American varieties. The immunoglobulin E (IgE)-binding ability of different processed peanuts to IgE was not significantly different. Therefore, peanut varieties may induce different amounts of allergens. The relative lower contents of Ara h 1 and Ara h 3 may lead to the lower prevalence of peanut allergy.

语种: 英语
WOS记录号: WOS:000256156800005
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/52792
Appears in Collections:北京大学第三临床医学院_皮肤科_期刊论文

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作者单位: 1.China Agr Univ, Coll Food Sci & Nutrit Engn, Beijing 100083, Peoples R China
2.Peking Univ, Third Hosp, Dept Dermatol, Beijing 100871, Peoples R China

Recommended Citation:
Cong, Yan-Jun,Lou, Fei,Li, Lin-Feng,et al. Identification and quantification of major peanut allergens (in China) with IgE-binding property[J]. JOURNAL OF FOOD BIOCHEMISTRY,2008,32(3):353-367.
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