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学科主题基础医学
An efficient non-iterative algorithm to estimate the apparent diffusion coefficient of water molecules in the magnetic resonance diffusion imaging experiments
Gao, Song1; Wang, Fei1,2; He, Dongqi2; Zhang, Shouyu3; Bao, Shanglian3
关键词Apparent diffusion coefficient Diffusion-weighted imaging DWI Non-iterative
刊名CHINESE SCIENCE BULLETIN
2014-03-01
DOI10.1007/s11434-013-0015-6
59期:8页:734-739
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Multidisciplinary Sciences
研究领域[WOS]Science & Technology - Other Topics
关键词[WOS]HUMAN BRAIN ; WHITE-MATTER ; MODEL
英文摘要

Many studies have shown that the magnetic resonance signal decay with an extend range of diffusion weighting (b-factor) is a bi-exponential attenuation in the diffusion-weighted magnetic resonance imaging experiments in vivo. Based on this feature and the two-compartmental model, we propose a twice-linear-fitting (TLF) algorithm to estimate the apparent diffusion coefficient (ADC) of the water molecules instead of the commonly used iterative Levenberg-Marquardt (LM) method. The TLF algorithm consists of two liner fitting steps to estimate the fast and the slow apparent diffusion coefficients and their sizes, respectively. It is unnecessary to guess the initial values in the whole fitting process. The time consumption of the TLF algorithm is much less than that of the iterative LM method. Moreover, the TLF algorithm may avoid the extraneous solutions, which often deteriorates the results of the LM method. Compared with the iterative fitting method, the TLF algorithm is a reliable and time-efficient approach to estimate the ADC of water molecules in vivo in magnetic resonance diffusion-weighted imaging experiments.

语种英语
WOS记录号WOS:000331564100004
项目编号81171330 ; 7102102
资助机构National Natural Science Foundation of China ; Beijing Natural Science Foundation
引用统计
被引频次:1[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
版本出版稿
条目标识符http://ir.bjmu.edu.cn/handle/400002259/52811
专题北京大学基础医学院_生物物理学系
医学人文研究院/公共教学部_哲学与社会科学系
作者单位1.Peking Univ, Hlth Sci Ctr, Dept Phys, Beijing 100191, Peoples R China
2.Peking Univ, Sch Basic Med Sci, Dept Biophys, Beijing 100191, Peoples R China
3.Peking Univ, Sch Phys, Med Phys & Engn Lab, Beijing 100875, Peoples R China
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GB/T 7714
Gao, Song,Wang, Fei,He, Dongqi,et al. An efficient non-iterative algorithm to estimate the apparent diffusion coefficient of water molecules in the magnetic resonance diffusion imaging experiments[J]. CHINESE SCIENCE BULLETIN,2014,59(8):734-739.
APA Gao, Song,Wang, Fei,He, Dongqi,Zhang, Shouyu,&Bao, Shanglian.(2014).An efficient non-iterative algorithm to estimate the apparent diffusion coefficient of water molecules in the magnetic resonance diffusion imaging experiments.CHINESE SCIENCE BULLETIN,59(8),734-739.
MLA Gao, Song,et al."An efficient non-iterative algorithm to estimate the apparent diffusion coefficient of water molecules in the magnetic resonance diffusion imaging experiments".CHINESE SCIENCE BULLETIN 59.8(2014):734-739.
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