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学科主题: 药学
题名:
Nonsteroidal Anti-Inflammatory Drugs Versus Corticosteroid for Treatment of Shoulder Pain: A Systematic Review and Meta-Analysis
作者: Zheng, Xiao-Qing1; Li, Ke2; Wei, You-Dong3; Tie, Hong-Tao4; Yi, Xiao-Yan5; Huang, Wei2
关键词: Corticosteroids ; Meta-Analysis ; NSAIDs ; Rehabilitation ; Shoulder pain
刊名: ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION
发表日期: 2014-10-01
DOI: 10.1016/j.apmr.2014.04.024
卷: 95, 期:10, 页:1824-1831
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Rehabilitation ; Sport Sciences
研究领域[WOS]: Rehabilitation ; Sport Sciences
关键词[WOS]: ROTATOR CUFF TENDINITIS ; ADHESIVE CAPSULITIS ; DOUBLE-BLIND ; SUBACROMIAL INJECTION ; FROZEN SHOULDER ; RANDOMIZED-TRIALS ; DISORDERS ; COMMUNITY ; IMPINGEMENT ; SYMPTOMS
英文摘要:

Objective: To compare the treatment efficacy between corticosteroid injection and nonsteroidal anti-inflammatory drugs (NSAIDs) for patients with shoulder pain.

Data Sources: PubMed and EMBASE databases were searched from inception to January 2014. Reference lists of the retrieved studies were additionally scrutinized.

Study Selection: Randomized controlled trials (RCTs) comparing corticosteroid injection with NSAIDs for treatment of shoulder pain were included. The primary outcome was remission, and the secondary outcomes were pain relief and improvement of range of active abduction. Study selection was conducted by 2 researchers independently. Any disagreements were solved by discussion and confirmed by the third reviewer.

Data Extraction: Two reviewers independently conducted data extraction and the quality assessment. Data regarding patients, intervention, control, and outcomes were extracted from the included trials.

Data Synthesis: Six high-quality RCTs of 267 patients meeting the inclusion criteria were included. For an outcome of remission, NSAIDs were less effective than corticosteroid in 4 or 6 weeks (relative risk, .64; 95% confidence interval,.45-.92). NSAIDs did not significantly differ with corticosteroid in pain relief and improvement of range of active abduction.

Conclusions: Current meta-analysis suggests that NSAEDs are less effective than corticosteroid in achieving remission in patients with shoulder pain at 4 or 6 weeks after treatment. Considering the limited number of studies and small size of each trial, the results should be interpreted with caution, and more high-quality RCTs are encouraged. (C) 2014 by the American Congress of Rehabilitation Medicine

语种: 英语
WOS记录号: WOS:000342542900004
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/52828
Appears in Collections:北京大学药学院_化学生物学系_期刊论文

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作者单位: 1.Peking Univ, Hlth Sci Ctr, Sch Pharmaceut Sci, Dept Biol Chem, Beijing 100871, Peoples R China
2.Chongqing Med Univ, Affiliated Hosp 1, Dept Orthopaed Surg, Chongqing 400016, Peoples R China
3.Chongqing Med Univ, Affiliated Hosp 1, Dept Neurol, Chongqing 400016, Peoples R China
4.Chongqing Med Univ, Affiliated Hosp 1, Dept Cardiothorac Surg, Chongqing 400016, Peoples R China
5.Chongqing Med Univ, Affiliated Hosp 1, Dept Endocrinol, Chongqing 400016, Peoples R China

Recommended Citation:
Zheng, Xiao-Qing,Li, Ke,Wei, You-Dong,et al. Nonsteroidal Anti-Inflammatory Drugs Versus Corticosteroid for Treatment of Shoulder Pain: A Systematic Review and Meta-Analysis[J]. ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION,2014,95(10):1824-1831.
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