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学科主题: 临床医学
题名:
Management of recurrent alveolar soft-part sarcoma of the tongue after external beam radiotherapy with iodine-125 seed brachytherapy
作者: Meng, Na1; Zhang, Xiaomeng2; Liao, Anyan1; Tian, Suqing1; Ran, Weiqiang3; Gao, Yang1; Wang, Jun Jie1
关键词: I-125 seed ; brachytherapy ; ultrasound guidance ; alveolar soft-part sarcoma ; outcome
刊名: HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK
发表日期: 2014-12-01
DOI: 10.1002/hed.23648
卷: 36, 期:12, 页:E125-E128
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Otorhinolaryngology ; Surgery
研究领域[WOS]: Otorhinolaryngology ; Surgery
关键词[WOS]: IMPLANTATION ; CHILDREN ; HEAD ; NECK
英文摘要:

BackgroundAlveolar soft part sarcoma (ASPS) is a rare type of soft tissue sarcoma. The infrequency of ASPS is such that it accounts for <1% of all soft tissue sarcomas and <0.1% of sarcomas concerning the head and neck, primarily those involving the orbit (48%) and tongue (25%). Traditional chemotherapy or radiotherapy of ASPS is often associated with poor outcome, even after comprehensive interventions.

Methods and ResultsWe performed iodine-125 (I-125) seed brachytherapy under ultrasound guidance through a submandibular puncture in a 4-year-old boy with recurrent ASPS of the tongue. The prescription dose was 120 Gy; therefore, 35 I-125 seeds were implanted with 0.77 mCi per seed, the total amount of activity being 26.95 mCi. CT scans confirmed a complete response after the treatment.

ConclusionOur patient now has a recurrent-free survival of >30 months, an amount of time longer than the median rate described in the literature. (c) 2014 Wiley Periodicals, Inc. Head Neck 36: E125-E128, 2014

语种: 英语
WOS记录号: WOS:000344801200001
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/52887
Appears in Collections:北京大学第三临床医学院_肿瘤放疗科_期刊论文

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作者单位: 1.Peking Univ Third Hosp, Dept Radiat Oncol, Beijing 100191, Peoples R China
2.Harvard Univ, Massachusetts Gen Hosp, Sch Med, Ctr Adv Med Imaging Sci, Boston, MA 02115 USA
3.Peking Univ Third Hosp, Dept Ultrasound, Beijing 100191, Peoples R China

Recommended Citation:
Meng, Na,Zhang, Xiaomeng,Liao, Anyan,et al. Management of recurrent alveolar soft-part sarcoma of the tongue after external beam radiotherapy with iodine-125 seed brachytherapy[J]. HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK,2014,36(12):E125-E128.
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