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学科主题: 临床医学
题名:
Rectal hypersensitivity reduced by acupoint TENS in patients with diarrhea-predominant irritable bowel syndrome: A pilot study
作者: Xiao, WB; Liu, YL
关键词: irritable bowel syndrome ; visceral hypersensitivity ; TENS
刊名: DIGESTIVE DISEASES AND SCIENCES
发表日期: 2004-02-01
卷: 49, 期:2, 页:312-319
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Gastroenterology & Hepatology
研究领域[WOS]: Gastroenterology & Hepatology
关键词[WOS]: SACRAL NERVE-STIMULATION ; PLACEBO-CONTROLLED TRIAL ; OPIOID RECEPTORS ; PAIN SENSITIVITY ; DOUBLE-BLIND ; IBS PATIENTS ; CONSTIPATION ; DISTENSION ; PERCEPTION ; SYMPTOMS
英文摘要:

Our aim was to compare rectal perception of patients with diarrhea-predominant irritable bowel syndrome (IBS-D), constipation-predominant irritable bowel syndrome (IBS-C), functional constipation (FC), and healthy controls and to evaluate the therapeutic effect of acupoint transcutaneous electric nerve stimulation (TENS). Age- and sex-matched patients (24 IBS-D, 20 IBS-C, and 30 FC) were selected, and 30 volunteers served as healthy controls. Rectal sensory thresholds were evaluated by rectal balloon distension. Short- and long-term acupoint TENS was given respectively. IBS-D patients had significantly lower rectal sensory thresholds of the first sensation of stool, urgency of defecation, and pain than IBS-C or FC patients or healthy controls (P<0.05), but there were no differences in rectal sensory thresholds among IBS-C and FC patients and healthy controls. In each group, females had significantly lower rectal sensory thresholds than males (P<0.05), but there was no difference between younger (less than or equal to50 years old) and older (>50 years old) patients. Short- term acupoint TENS increased rectal sensory thresholds of IBS-D patients. After 2-month acupoint TENS treatment in IBS-D patients, rectal sensory thresholds were significantly increased, stool times and the intensity of abdominal pain were decreased, and psychological scores were relieved to normal. Lowered rectal perception threshold is a hallmark of IBS-D patients. Females have significantly lower rectal sensory thresholds than males. Acupoint TENS is effective to treat IBS-D.

语种: 英语
WOS记录号: WOS:000189235100025
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/52907
Appears in Collections:北京大学第二临床医学院_消化内科_期刊论文

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作者单位: Peking Univ, Peoples Hosp, Dept Gastroenterol, Beijing 100044, Peoples R China

Recommended Citation:
Xiao, WB,Liu, YL. Rectal hypersensitivity reduced by acupoint TENS in patients with diarrhea-predominant irritable bowel syndrome: A pilot study[J]. DIGESTIVE DISEASES AND SCIENCES,2004,49(2):312-319.
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