| 学科主题 | 药学 |
| Diastereoselective formation of aziridines from diazocarbonyl compounds and N-(O-pivaloylated D-galactosyl) benzylideneamines and ring-opening reactions with p-toluenethiol | |
| Zhao, Yizhou1; Wang, Gang1; Zhou, Shanshan1; Li, Zhongjun1; Meng, Xiangbao1 | |
| 刊名 | ORGANIC & BIOMOLECULAR CHEMISTRY
 |
| 2014 | |
| DOI | 10.1039/c4ob00443d |
| 卷 | 12期:21页:3362-3365 |
| 收录类别 | SCI ; IC ; CCR |
| 文章类型 | Article |
| WOS标题词 | Science & Technology |
| 类目[WOS] | Chemistry, Organic |
| 资助者 | National Natural Science Foundation of China ; National Basic Research Program of China ; National Natural Science Foundation of China ; National Basic Research Program of China |
| 研究领域[WOS] | Chemistry |
| 关键词[WOS] | MANNICH-MICHAEL REACTIONS ; ASYMMETRIC-SYNTHESIS ; STEREOSELECTIVE-SYNTHESIS ; CHIRAL TEMPLATES ; UGI-SYNTHESIS ; CARBOHYDRATE TEMPLATES ; CATALYZED SYNTHESIS ; LEWIS-ACID ; DERIVATIVES ; ALKALOIDS |
| 英文摘要 | N-Galactosyl aziridines were synthesized via BF3 center dot OEt2 promoted addition of carbenes generated from diazocarbonyl compounds with O-pivaloylated beta-D-galactosylimines in good yields and high diastereoselectivity. The ring-opening reactions with p-toluenethiol of the aziridines provided enantiometrically pure beta-S-substituted phenylalanine derivatives in a highly regioselective manner. |
| 语种 | 英语 |
| 所属项目编号 | 21072017 ; 2012CB822100 |
| 资助者 | National Natural Science Foundation of China ; National Basic Research Program of China ; National Natural Science Foundation of China ; National Basic Research Program of China |
| WOS记录号 | WOS:000336023400008 |
| Citation statistics | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.bjmu.edu.cn/handle/400002259/52910 |
| Collection | 北京大学药学院 |
| 作者单位 | 1.Peking Univ, Sch Pharmaceut Sci, State Key Lab Nat & Biomimet Drugs, Beijing 100191, Peoples R China 2.Peking Univ, Sch Pharmaceut Sci, Dept Biol Chem, Beijing 100191, Peoples R China |
| Recommended Citation GB/T 7714 | Zhao, Yizhou,Wang, Gang,Zhou, Shanshan,et al. Diastereoselective formation of aziridines from diazocarbonyl compounds and N-(O-pivaloylated D-galactosyl) benzylideneamines and ring-opening reactions with p-toluenethiol[J]. ORGANIC & BIOMOLECULAR CHEMISTRY,2014,12(21):3362-3365. |
| APA | Zhao, Yizhou,Wang, Gang,Zhou, Shanshan,Li, Zhongjun,&Meng, Xiangbao.(2014).Diastereoselective formation of aziridines from diazocarbonyl compounds and N-(O-pivaloylated D-galactosyl) benzylideneamines and ring-opening reactions with p-toluenethiol.ORGANIC & BIOMOLECULAR CHEMISTRY,12(21),3362-3365. |
| MLA | Zhao, Yizhou,et al."Diastereoselective formation of aziridines from diazocarbonyl compounds and N-(O-pivaloylated D-galactosyl) benzylideneamines and ring-opening reactions with p-toluenethiol".ORGANIC & BIOMOLECULAR CHEMISTRY 12.21(2014):3362-3365. |
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