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学科主题: 临床医学
题名:
Comparison of the prevalence of chronic kidney disease among different ethnicities: Beijing CKD survey and American NHANES
作者: Xu, Rong1; Zhang, Luxia1; Zhang, PuHong2,3; Wang, Fang1; Zuo, Li1; Wang, HaiYan1
关键词: albuminuria ; chronic kidney disease ; chronic renal insufficiency ; ethnicity
刊名: NEPHROLOGY DIALYSIS TRANSPLANTATION
发表日期: 2009-04-01
DOI: 10.1093/ndt/gfn609
卷: 24, 期:4, 页:1220-1226
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Transplantation ; Urology & Nephrology
研究领域[WOS]: Transplantation ; Urology & Nephrology
关键词[WOS]: STAGE RENAL-DISEASE ; GLOMERULAR-FILTRATION-RATE ; RACIAL-DIFFERENCES ; METABOLIC SYNDROME ; UNITED-STATES ; SOCIOECONOMIC-STATUS ; POPULATION ; RACE ; MICROALBUMINURIA ; HYPERTENSION
英文摘要:

Background. It is unclear whether ethnic disparity of the prevalence of chronic kidney disease (CKD) exists among native Chinese and American ethnicities.

Methods. A stratified multistage clustered screening for CKD performed in Beijing in 2006 was compared with data from the National Health and Nutrition Examination Survey (NHANES) between 1999-2006 (participants aged >= 20 years, 13 626 Chinese, 9006 whites, 3447 African Americans, 4626 Hispanics). Serum creatinine from Beijing and NHANES were calibrated at the Cleveland Clinic Laboratory. The re-expressed abbreviated MDRD equation for Americans and its modified form for Chinese were used to estimate glomerular filtration rate (eGFR). Subjects with eGFR <60 mL/min/1.73 m(2) were diagnosed as having chronic renal insufficiency (CRI). Albuminuria was diagnosed if the urine albumin-creatinine ratio was >17 mg/g for males or >25 mg/g for females. CKD was diagnosed if CRI or albuminuria was present.

Results. Compared with American whites, African Americans and Hispanics, Chinese had a lower prevalence of adjusted albuminuria (12.10%, 16.33% and 14.16% versus 9.27%), CRI (9.46%, 5.18% and 3.11% versus 1.38%) and CKD (19.03%, 19.00% and 15.99% versus 10.25%). Moreover, Chinese hold the lowest risk of albuminuria when exposed to diabetes; the risk of CRI among Chinese when exposed to diabetes or hypertension was lower than that among African Americans, but similar to that among whites and Hispanics.

Conclusions. The CKD prevalence was significantly different among native Chinese and American ethnicities.

语种: 英语
WOS记录号: WOS:000264398800025
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/52911
Appears in Collections:北京大学第一临床医学院_肾脏内科_期刊论文

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作者单位: 1.Ctr Prevent Med Res, Beijing, Peoples R China
2.Peking Univ, Hosp 1, Inst Nephrol, Beijing 100034, Peoples R China
3.Beijing Ctr Dis Control & Prevent CDC, Beijing, Peoples R China

Recommended Citation:
Xu, Rong,Zhang, Luxia,Zhang, PuHong,et al. Comparison of the prevalence of chronic kidney disease among different ethnicities: Beijing CKD survey and American NHANES[J]. NEPHROLOGY DIALYSIS TRANSPLANTATION,2009,24(4):1220-1226.
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