北京大学医学部机构知识库
Advanced  
IR@PKUHSC  > 北京大学药学院  > 期刊论文
学科主题: 药学
题名:
Phosphane-Free Copper-Catalyzed Decarboxylative Coupling of Alkynyl Carboxylic Acids with Aryl Halides under Aerobic Conditions
作者: Pan, Delin1; Zhang, Chun1; Ding, Shengtao1; Jiao, Ning1,2
关键词: Cross-coupling ; Copper ; Decarboxylation ; Carboxylic acids ; O ligands
刊名: EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
发表日期: 2011-09-01
DOI: 10.1002/ejoc.201100659
期: 25, 页:4751-4755
收录类别: SCI ; IC ; CCR
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Chemistry, Organic
研究领域[WOS]: Chemistry
关键词[WOS]: IRON/COPPER COCATALYZED ALKYNYLATION ; ALPHA-OXOCARBOXYLIC ACIDS ; PALLADIUM-FREE CONDITIONS ; ONE-POT SYNTHESIS ; TERMINAL ALKYNES ; SONOGASHIRA REACTION ; SUZUKI-MIYAURA ; BOND FORMATION ; VINYL HALIDES ; C-C
英文摘要:

A phosphane-free copper-catalyzed decarboxylative cross-coupling reaction of alkynyl carboxylic acids with aryl halides was developed. CuBr (1-5 mol-%) was used as a catalyst in the presence of a beta-diketone ligand in air. The reactions of aryl iodides were conducted in the absence of a Pd catalyst. The ligand plays a key role in this kind of copper catalysis. NaNO(2) was disclosed to efficiently improve this kind of decarboxylative cross-coupling when a nitro group was not present in the substrates.

语种: 英语
所属项目编号: 20872003 ; 2009CB825300
项目资助者: National Natural Science Foundation of China ; National Basic Research Program of China (973 Program) ; Program for New Century Excellent Talents in University (NCET)
WOS记录号: WOS:000295211500004
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/52924
Appears in Collections:北京大学药学院_期刊论文

Files in This Item:

There are no files associated with this item.


作者单位: 1.Peking Univ, State Key Lab Nat & Biomimet Drugs, Sch Pharmaceut Sci, Beijing 100191, Peoples R China
2.E China Normal Univ, Shanghai Key Lab Green Chem & Chem Proc, Dept Chem, Shanghai 200062, Peoples R China

Recommended Citation:
Pan, Delin,Zhang, Chun,Ding, Shengtao,et al. Phosphane-Free Copper-Catalyzed Decarboxylative Coupling of Alkynyl Carboxylic Acids with Aryl Halides under Aerobic Conditions[J]. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY,2011(25):4751-4755.
Service
Recommend this item
Sava as my favorate item
Show this item's statistics
Export Endnote File
Google Scholar
Similar articles in Google Scholar
[Pan, Delin]'s Articles
[Zhang, Chun]'s Articles
[Ding, Shengtao]'s Articles
CSDL cross search
Similar articles in CSDL Cross Search
[Pan, Delin]‘s Articles
[Zhang, Chun]‘s Articles
[Ding, Shengtao]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Copyright © 2007-2017  北京大学医学部 - Feedback
Powered by CSpace