|Effect of negative emotions evoked by light, noise and taste on trigeminal thermal sensitivity|
|Yang, Guangju1,2; Baad-Hansen, Lene3; Wang, Kelun4; Xie, Qiu-Fei1,2; Svensson, Peter3,5|
|关键词||Quantitative Sensory Testing Affective State Thermal Sensitivity Light Noise Taste|
|刊名||JOURNAL OF HEADACHE AND PAIN|
|WOS标题词||Science & Technology|
|类目[WOS]||Clinical Neurology ; Neurosciences|
|研究领域[WOS]||Neurosciences & Neurology|
|关键词[WOS]||AFFECTIVE PICTURE MODULATION ; MULTISENSORY INTEGRATION ; CUTANEOUS ALLODYNIA ; CLASSICAL-MUSIC ; MUSCLE PAIN ; TIME-COURSE ; MIGRAINE ; POTENTIATION ; ATTENTION ; NEURONS|
Patients with migraine often have impaired somatosensory function and experience headache attacks triggered by exogenous stimulus, such as light, sound or taste. This study aimed to assess the influence of three controlled conditioning stimuli (visual, auditory and gustatory stimuli and combined stimuli) on affective state and thermal sensitivity in healthy human participants.
All participants attended four experimental sessions with visual, auditory and gustatory conditioning stimuli and combination of all stimuli, in a randomized sequence. In each session, the somatosensory sensitivity was tested in the perioral region with use of thermal stimuli with and without the conditioning stimuli. Positive and Negative Affect States (PANAS) were assessed before and after the tests. Subject based ratings of the conditioning and test stimuli in addition to skin temperature and heart rate as indicators of arousal responses were collected in real time during the tests.
The three conditioning stimuli all induced significant increases in negative PANAS scores (paired t-test, P a parts per thousand currency sign0.016). Compared with baseline, the increases were in a near dose-dependent manner during visual and auditory conditioning stimulation. No significant effects of any single conditioning stimuli were observed on trigeminal thermal sensitivity (P a parts per thousand yen0.051) or arousal parameters (P a parts per thousand yen0.057). The effects of combined conditioning stimuli on subjective ratings (P a parts per thousand currency sign0.038) and negative affect (P = 0.011) were stronger than those of single stimuli.
All three conditioning stimuli provided a simple way to evoke a negative affective state without physical arousal or influence on trigeminal thermal sensitivity. Multisensory conditioning had stronger effects but also failed to modulate thermal sensitivity, suggesting that so-called exogenous trigger stimuli e.g. bright light, noise, unpleasant taste in patients with migraine may require a predisposed or sensitized nervous system.
|资助机构||Danish Dental Association|
|作者单位||1.Aarhus Univ, Sect Clin Oral Physiol, Dept Dent, Aarhus, Denmark|
2.Karolinska Inst, Dept Dent Med, Huddinge, Sweden
3.Peking Univ, Sch & Hosp Stomatol, Dept Prosthodont, Beijing 100081, Peoples R China
4.Peking Univ, Sch & Hosp Stomatol, Ctr Oral Funct Diag Treatment & Res, Beijing 100081, Peoples R China
5.Aalborg Univ, Ctr Sensory Motor Interact SMI, Dept Hlth Sci & Technol, Aalborg, Denmark
|Yang, Guangju,Baad-Hansen, Lene,Wang, Kelun,et al. Effect of negative emotions evoked by light, noise and taste on trigeminal thermal sensitivity[J]. JOURNAL OF HEADACHE AND PAIN,2014,15:1-12.|
|APA||Yang, Guangju,Baad-Hansen, Lene,Wang, Kelun,Xie, Qiu-Fei,&Svensson, Peter.(2014).Effect of negative emotions evoked by light, noise and taste on trigeminal thermal sensitivity.JOURNAL OF HEADACHE AND PAIN,15,1-12.|
|MLA||Yang, Guangju,et al."Effect of negative emotions evoked by light, noise and taste on trigeminal thermal sensitivity".JOURNAL OF HEADACHE AND PAIN 15(2014):1-12.|