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学科主题: 临床医学
题名:
Epidemiology, diagnosis and management of hirsutism: a consensus statement by the Androgen Excess and Polycystic Ovary Syndrome Society
作者: Escobar-Morreale, H. F.1,2,3,4; Carmina, E.5; Dewailly, D.6; Gambineri, A.7; Kelestimur, F.8; Moghetti, P.9,10; Pugeat, M.11; Qiao, J.12; Wijeyaratne, C. N.13; Witchel, S. F.14; Norman, R. J.15
关键词: hirsutism ; androgen excess ; terminal hair ; polycystic ovary syndrome ; guidelines
刊名: HUMAN REPRODUCTION UPDATE
发表日期: 2012-03-01
DOI: 10.1093/humupd/dmr042
卷: 18, 期:2, 页:146-170
收录类别: SCI
文章类型: Review
WOS标题词: Science & Technology
类目[WOS]: Obstetrics & Gynecology ; Reproductive Biology
研究领域[WOS]: Obstetrics & Gynecology ; Reproductive Biology
关键词[WOS]: CONGENITAL ADRENAL-HYPERPLASIA ; RANDOMIZED CONTROLLED-TRIAL ; LONG-TERM TREATMENT ; LOW-DOSE FLUTAMIDE ; 3RD-GENERATION ORAL-CONTRACEPTIVES ; SPIRONOLACTONE PLUS FINASTERIDE ; ESTRADIOL-CYPROTERONE ACETATE ; CONTROLLED CLINICAL-TRIAL ; HORMONE-BINDING GLOBULIN ; LIFE-STYLE MODIFICATION
英文摘要:

Hirsutism, defined by the presence of excessive terminal hair in androgen-sensitive areas of the female body, is one of the most common disorders in women during reproductive age.

We conducted a systematic review and critical assessment of the available evidence pertaining to the epidemiology, pathophysiology, diagnosis and management of hirsutism.

The prevalence of hirsutism is approximate to 10 in most populations, with the important exception of Far-East Asian women who present hirsutism less frequently. Although usually caused by relatively benign functional conditions, with the polycystic ovary syndrome leading the list of the most frequent etiologies, hirsutism may be the presenting symptom of a life-threatening tumor requiring immediate intervention.

Following evidence-based diagnostic and treatment strategies that address not only the amelioration of hirsutism but also the treatment of the underlying etiology is essential for the proper management of affected women, especially considering that hirsutism is, in most cases, a chronic disorder needing long-term follow-up. Accordingly, we provide evidence-based guidelines for the etiological diagnosis and for the management of this frequent medical complaint.

语种: 英语
WOS记录号: WOS:000300722000004
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/53043
Appears in Collections:北京大学第三临床医学院_期刊论文

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作者单位: 1.Hosp Univ Ramon y Cajal, Dept Endocrinol, Diabet Obes & Human Reprod Res Grp, Madrid 28034, Spain
2.Univ Alcala De Henares, Madrid 28034, Spain
3.Inst Ramon y Cajal Invest Sanitaria IRYCIS, Madrid 28034, Spain
4.CIBER Diabet & Enfermedades Metabol Asociadas CIB, Madrid 28034, Spain
5.Univ Verona, Dept Med, I-37126 Verona, Italy
6.Azienda Osped Univ Integrata Verona, I-37126 Verona, Italy
7.Univ Palermo, Endocrine Unit, Dept Biol & Med Sci, I-90139 Palermo, Italy
8.CHRU, Dept Endocrine Gynaecol & Reprod Med, Hop Jeanne Flandre, F-59037 Lille, France
9.Univ Alma Mater Studiorum, Div Endocrinol, Dept Clin Med, St Orsola Malpighi Hosp, I-40138 Bologna, Italy
10.Erciyes Univ, Dept Endocrinol, Sch Med, TR-38039 Kayseri, Turkey
11.Univ Lyon 1, Endocrinol Unit, Dept Med, INSERM U,Hosp Civils Lyon, F-69673 Lyon, France
12.Peking Univ, Dept Obstet & Gynecol, Hosp 3, Beijing 100083, Peoples R China
13.Univ Colombo, Dept Obstet & Gynecol, Fac Med, Colombo, Sri Lanka
14.Univ Pittsburgh, Div Pediat Endocrinol, Childrens Hosp Pittsburgh, Pittsburgh, PA 15224 USA
15.Univ Adelaide, Robinson Inst, Sch Pediat & Reprod Hlth, Adelaide, SA 5005, Australia

Recommended Citation:
Escobar-Morreale, H. F.,Carmina, E.,Dewailly, D.,et al. Epidemiology, diagnosis and management of hirsutism: a consensus statement by the Androgen Excess and Polycystic Ovary Syndrome Society[J]. HUMAN REPRODUCTION UPDATE,2012,18(2):146-170.
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