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学科主题: 临床医学
题名:
A "loop" shape descriptor and its application to automated segmentation of airways from CT scans
作者: Pu, Jiantao1,2; Jin, Chenwang1; Yu, Nan1; Qian, Yongqiang1; Wang, Xiaohua3; Meng, Xin4; Guo, Youmin1
关键词: airways ; tubular structure ; shape descriptor ; loop ; vessels ; CT
刊名: MEDICAL PHYSICS
发表日期: 2015-06-01
DOI: 10.1118/1.4921139
卷: 42, 期:6, 页:3076-3084
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Radiology, Nuclear Medicine & Medical Imaging
研究领域[WOS]: Radiology, Nuclear Medicine & Medical Imaging
关键词[WOS]: VIRTUAL BRONCHOSCOPY ; IMAGES ; TREES ; RECONSTRUCTION ; EMPHYSEMA ; DISEASE ; OBSTRUCTION ; OBJECTS
英文摘要:

Purpose: A novel shape descriptor is presented to aid an automated identification of the airways depicted on computed tomography (CT) images.

Methods: Instead of simplifying the tubular characteristic of the airways as an ideal mathematical cylindrical or circular shape, the proposed "loop" shape descriptor exploits the fact that the cross sections of any tubular structure (regardless of its regularity) always appear as a loop. In implementation, the authors first reconstruct the anatomical structures in volumetric CT as a three-dimensional surface model using the classical marching cubes algorithm. Then, the loop descriptor is applied to locate the airways with a concave loop cross section. To deal with the variation of the airway walls in density as depicted on CT images, a multiple threshold strategy is proposed. A publicly available chest CT database consisting of 20 CT scans, which was designed specifically for evaluating an airway segmentation algorithm, was used for quantitative performance assessment. Measures, including length, branch count, and generations, were computed under the aid of a skeletonization operation.

Results: For the test dataset, the airway length ranged from 64.6 to 429.8 cm, the generation ranged from 7 to 11, and the branch number ranged from 48 to 312. These results were comparable to the performance of the state-of-the-art algorithms validated on the same dataset.

Conclusions: The authors′ quantitative experiment demonstrated the feasibility and reliability of the developed shape descriptor in identifying lung airways. (C) 2015 American Association of Physicists in Medicine.

语种: 英语
WOS记录号: WOS:000356998300033
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/53077
Appears in Collections:北京大学第三临床医学院_期刊论文

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作者单位: 1.Peking Univ, Affiliated Hosp 3, Beijing 100029, Peoples R China
2.Xi An Jiao Tong Univ, Dept Radiol, Affiliated Hosp 1, Coll Med, Shaanxi 710061, Peoples R China
3.Univ Pittsburgh, Dept Radiol & Bioengn, Pittsburgh, PA 15213 USA
4.Univ Pittsburgh, Dept Radiol, Pittsburgh, PA 15213 USA

Recommended Citation:
Pu, Jiantao,Jin, Chenwang,Yu, Nan,et al. A "loop" shape descriptor and its application to automated segmentation of airways from CT scans[J]. MEDICAL PHYSICS,2015,42(6):3076-3084.
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