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学科主题临床医学
Experience with wound complications after surgery for sacral tumors
Li, Dasen; Guo, Wei; Qu, Huayi; Yang, Rongli; Tang, Xiaodong; Yan, Taiqiang; Tang, Shun; Yang, Yi; Ji, Tao; Dong, Sen
关键词Sacrum Tumor Risk Factors Surgical Site Infection Wound Dehiscence Surgery
刊名EUROPEAN SPINE JOURNAL
2013-09-01
DOI10.1007/s00586-013-2765-x
22期:9页:2069-2076
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Clinical Neurology ; Orthopedics
研究领域[WOS]Neurosciences & Neurology ; Orthopedics
关键词[WOS]TOTAL SACRECTOMY ; SURGICAL-TREATMENT ; RECONSTRUCTION ; SPINE ; IRRADIATION ; INFECTIONS ; MANAGEMENT ; RESECTION ; CHORDOMA ; HEAD
英文摘要

The aim of this article is to summarize our experience in treating sacral wound complications after sacrectomy. We focus, in particular, on factors associated with wound complications, including surgical site infection (SSI) and wound dehiscence.

The definition of SSI devised by Horgan et al. was applied. Wound dehiscence was defined as a wound showing breakdown in the absence of clinical signs meeting the diagnostic standard for SSI. Between September 1997 and August 2009, 387 patients with a sacral tumor underwent sacrectomy performed by the same team of surgeons and were followed up for a parts per thousand yen12 months. Potential risk factors were evaluated for univariate associations with SSI and wound complications. Multivariable conditional logistic regression was used to identify the combined effects of several risk factors.

Of the 387 wounds studied, 274 healed uneventfully, and 113 (29.2 %) broke down because of infection or dehiscence. Fifty-one (13.2 %) patients developed a postoperative SSI, and 62 (16.0 %) patients developed wound dehiscence. Gram-negative bacteria grew in 45 cultures (91.8 %) and included 38 cases of Escherichia coli. Previous radiation, rectum rupture, longer duration of surgery, and cerebrospinal fluid leakage were significantly associated with increased likelihood of developing an SSI. Previous radiation, rectum rupture, age < 40 years, history of diabetes mellitus, maximum tumor diameter a parts per thousand yen10 cm, and instrumentation used were risk factors for wound complications.

The incidence of wound complications is not so high at a musculoskeletal tumor center with surgeons experienced in treating sacral tumors. Controlling for these risk factors when possible may improve clinical outcomes.

语种英语
WOS记录号WOS:000324598400020
引用统计
被引频次:12[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/53081
专题北京大学第二临床医学院_骨肿瘤科
北京大学药学院_天然药物与仿生药物国家重点实验室
作者单位Peking Univ, Peoples Hosp, Musculoskeletal Tumor Ctr, Beijing 100044, Peoples R China
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GB/T 7714
Li, Dasen,Guo, Wei,Qu, Huayi,et al. Experience with wound complications after surgery for sacral tumors[J]. EUROPEAN SPINE JOURNAL,2013,22(9):2069-2076.
APA Li, Dasen.,Guo, Wei.,Qu, Huayi.,Yang, Rongli.,Tang, Xiaodong.,...&Dong, Sen.(2013).Experience with wound complications after surgery for sacral tumors.EUROPEAN SPINE JOURNAL,22(9),2069-2076.
MLA Li, Dasen,et al."Experience with wound complications after surgery for sacral tumors".EUROPEAN SPINE JOURNAL 22.9(2013):2069-2076.
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