北京大学医学部机构知识库
Advanced  
IR@PKUHSC  > 北京大学第一临床医学院  > 肾脏内科  > 期刊论文
学科主题: 临床医学
题名:
Risk Factors of Pulmonary Thrombosis/Embolism in Nephrotic Syndrome
作者: Yang, Yihe1,2,3,4; Lv, Jicheng1,2,3,4; Zhou, Fude1,2,3,4; Chen, Min1,2,3,4; Wang, Rongfu5; Zhao, Minghui2,3,4; Wang, Haiyan1,2,3,4
关键词: Risk Factors ; Pulmonary Thrombosis ; Embolism ; Nephrotic Syndrome
刊名: AMERICAN JOURNAL OF THE MEDICAL SCIENCES
发表日期: 2014-11-01
卷: 348, 期:5, 页:394-398
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Medicine, General & Internal
研究领域[WOS]: General & Internal Medicine
关键词[WOS]: RENAL-VEIN THROMBOSIS ; THROMBOEMBOLIC EVENTS ; MEMBRANOUS NEPHROPATHY ; VENOUS THROMBOEMBOLISM ; D-DIMER ; EMBOLISM ; COMPLICATIONS ; EXCLUSION ; OUTCOMES
英文摘要:

Background: Nephrotic syndrome is associated with an increased risk for thromboembolic complications. Until now, few studies have ever specified the risk of pulmonary thrombosis/embolism (PTE) in patients with nephrotic syndrome. In this study, we assessed the risk of PTE in a large cross-sectional study to identify risk factors in this population. Methods: Three hundred twelve patients with NS who had screened PTE through lung ventilation-perfusion scan were collected and analyzed. Multivariate Logistic regression was used to detect the independent risk factors for PTE. Logistic regression was used to identify the threshold value of D-dimer. Results: Sixty-five patients (20.8%) had PTE in individuals with NS. Elevated level of plasma D-dimer was identified as an independent risk factor of PTE on multivariate analysis (odds ratio 5 1.54; 95% confidence interval: 1.27-1.88). While proteinuria at presentation and serum albumin were not associated with PTE after adjusted for D-dimer (P>0.05). The cumulative probability of PTE was in a nearly linear association with the plasma D-dimer level even within the normal range. Based on the plasma D-dimer level, we had developed a concise model to predict the risk of pulmonary embolism using logistic curve. Conclusions: In adult patients with NS, high level of plasma D-dimer was closely associated with PTE, whereas proteinuria or serum albumin level was not in this study. Using plasma D-dimer level, we developed a concise model to predict the risk of PTE.

语种: 英语
WOS记录号: WOS:000344608400008
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/53094
Appears in Collections:北京大学第一临床医学院_肾脏内科_期刊论文

Files in This Item:

There are no files associated with this item.


作者单位: 1.Peking Univ, Hosp 1, Div Renal, Beijing 100871, Peoples R China
2.Peking Univ, Inst Nephrol, Beijing 100871, Peoples R China
3.Minist Hlth China, Key Lab Renal Dis, Beijing, Peoples R China
4.Minist Educ, Key Lab Chron Kidney Dis Prevent & Treatment, Beijing, Peoples R China
5.Peking Univ, Hosp 1, Dept Nucl Med, Beijing 100871, Peoples R China

Recommended Citation:
Yang, Yihe,Lv, Jicheng,Zhou, Fude,et al. Risk Factors of Pulmonary Thrombosis/Embolism in Nephrotic Syndrome[J]. AMERICAN JOURNAL OF THE MEDICAL SCIENCES,2014,348(5):394-398.
Service
Recommend this item
Sava as my favorate item
Show this item's statistics
Export Endnote File
Google Scholar
Similar articles in Google Scholar
[Yang, Yihe]'s Articles
[Lv, Jicheng]'s Articles
[Zhou, Fude]'s Articles
CSDL cross search
Similar articles in CSDL Cross Search
[Yang, Yihe]‘s Articles
[Lv, Jicheng]‘s Articles
[Zhou, Fude]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Copyright © 2007-2017  北京大学医学部 - Feedback
Powered by CSpace