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学科主题: 临床医学
题名:
Orthostatic Hypertension in Children and Adolescents with Postural Tachycardia Syndrome
作者: Zhang, Qingyou; Li, Jiawei; Xie, Yao; Zhao, Juan; Du, Junbao
关键词: autonomic nervous system ; tachycardia ; orthostatic hypertension ; children
刊名: JOURNAL OF TROPICAL PEDIATRICS
发表日期: 2014-12-01
DOI: 10.1093/tropej/fmu055
卷: 60, 期:6, 页:461-466
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Pediatrics ; Tropical Medicine
研究领域[WOS]: Pediatrics ; Tropical Medicine
关键词[WOS]: BLOOD-PRESSURE ; SODIUM-INTAKE ; CARDIOVASCULAR-DISEASE ; UNEXPLAINED SYNCOPE ; RISK ; DISORDERS
英文摘要:

Objective: We described a heterogenous group of children disabled by postural tachycardia syndrome (POTS) and evident orthostatic hypertension (OHT).

Methods: Twenty patients met the diagnostic criteria for POTS+OHT. Their clinical characteristics were compared with those in 76 patients with POTS alone and 20 healthy age-matched controls. Multivariate logistic regression analysis was used to identify independent risk factors for POTS+OHT.

Results: Supine systolic blood pressure (SBP) was lower in the POTS+OHT group than in the POTS group (p<0.05). Compared with the POTS group, the POTS+OHT group showed markedly increased upright SBP, upright heart rate (HR) and HR changes (p<0.05). Headache was more common in the POTS+OHT group than in the POTS group (p<0.05). Logistic regression analysis revealed that low supine SBP and headache were independent risk factors for OHT in POTS patients.

Conclusions: Headache and low supine SBP were the main clinical characteristics of a novel syndrome of POTS associated with OHT.

语种: 英语
所属项目编号: D121107001012051 ; 2012CB517806
项目资助者: Beijing Municipal Science and Technology Commission, China ; Major Basic Research Project of China
WOS记录号: WOS:000346035900010
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/53184
Appears in Collections:北京大学第一临床医学院_儿科_期刊论文

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作者单位: Peking Univ, Hosp 1, Dept Pediat, Beijing 100034, Peoples R China

Recommended Citation:
Zhang, Qingyou,Li, Jiawei,Xie, Yao,et al. Orthostatic Hypertension in Children and Adolescents with Postural Tachycardia Syndrome[J]. JOURNAL OF TROPICAL PEDIATRICS,2014,60(6):461-466.
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