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The application of mid-IR fiber optics to diagnosis of colon cancer in vivo and in situ
Yang, LM1; Xu, Z1; Zhang, YF1; Xu, YZ1; Zhou, S1; Zhang, NW1; Li, QB1; Liu, Z1; Wang, LX1; Zhou, WJ1; Xu, DF1; Song, ZF1; Weng, SF1; Wu, JG1
关键词Mid-ir Fiber Optics Ftir Cancer In Vivo And In Situ
刊名SPECTROSCOPY AND SPECTRAL ANALYSIS
2003-10-01
23期:5页:883-884
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Spectroscopy
研究领域[WOS]Spectroscopy
关键词[WOS]ORAL-TISSUES
英文摘要

In our previous study, we demonstrated that the malignant tissues of digestive system, including stomach, colon, esophagus, gallbladder etc., can be distinguished from the normal tissues using FT-Mid-IR methods. In the present investigation, we have been successful in realizing the detection of the tumor tissue of rectum in vivo and in situ. The consents of patients were obtained. This non-invasive measurement was performed during the operation process in Third Hospital, Peking University using a mid-IR Fiber Optics (Spectra-Tech Corporation) with WQF-500 FTIR Spectrometer of Beijing Second Optical Instrument Factory. Experimental results demonstrated that the spectral features of normal and malignant tissues with blood supplement are similar to those obtained from our previous in-vitro measurement. For example, the strong bands located near 1400 and 1100 cm(-1) in a tumor spectrum of patient s rectum, which were measured in vivo and in situ during operation, indicated the malignancy of the tumor. This recent result means that in-situ FTIR spectroscopic method with fiber optics can be developed as a non-invasive, rapid, accurate and in vivo technique for operating surgery.

语种中文
WOS记录号WOS:000186376200016
引用统计
被引频次:16[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/53221
专题北京大学第三临床医学院
北京大学第三临床医学院_普通外科
作者单位1.Peking Univ, Hosp 3, Beijing 100083, Peoples R China
2.Peking Univ, Coll Chem & Mol Engn, Dept Biol Chem, State Key Lab Rare Earth Mat Chem & Applicat, Beijing 100871, Peoples R China
3.Chinese Acad Sci, Inst Chem, Beijing 100080, Peoples R China
推荐引用方式
GB/T 7714
Yang, LM,Xu, Z,Zhang, YF,et al. The application of mid-IR fiber optics to diagnosis of colon cancer in vivo and in situ[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS,2003,23(5):883-884.
APA Yang, LM.,Xu, Z.,Zhang, YF.,Xu, YZ.,Zhou, S.,...&Wu, JG.(2003).The application of mid-IR fiber optics to diagnosis of colon cancer in vivo and in situ.SPECTROSCOPY AND SPECTRAL ANALYSIS,23(5),883-884.
MLA Yang, LM,et al."The application of mid-IR fiber optics to diagnosis of colon cancer in vivo and in situ".SPECTROSCOPY AND SPECTRAL ANALYSIS 23.5(2003):883-884.
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