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学科主题: 临床医学
题名:
Coal Dust Contiguity-induced Changes in the Concentration of TNF- and NF- B p65 on the Ocular Surface
作者: Sun, Zhaoyi1,2; Hong, Jing1,3; Liu, Zaiying2; Jin, Xiudong2; Gu, Changhong2
关键词: coal dust ; xerophthalmia ; tumor necrosis factor-alpha ; nuclear factor-kappa B ; coal dust exposure
刊名: OCULAR IMMUNOLOGY AND INFLAMMATION
发表日期: 2009
DOI: 10.1080/09273940802650380
卷: 17, 期:2, 页:76-82
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Ophthalmology
研究领域[WOS]: Ophthalmology
关键词[WOS]: DRY EYE SYNDROME ; FACTOR-KAPPA-B ; XEROPHTHALMIA ; CANCER
英文摘要:

To observe the influence of coal dust on ocular surface of coal miners and rabbits with coal dust contiguity on expression TNF- and NF- Bp65 and dry eye occurrence. Tear production, BUT and lysozyme decreased for coal miners and rabbits with coal dust contiguity. Expression TNF- and NF- Bp65 in ocular surface were determined. Results showed tear production, BUT and lysozyme decreased for coal miners and rabbits with coal dust contiguity. Coal dust exposure was linked to development of xerophthalmia, and induced a higher expression of NF- B p65 and TNF- perhaps as a mechanism to resist coal dust ocular surface injury.

语种: 英语
WOS记录号: WOS:000265658500003
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/53223
Appears in Collections:北京大学第三临床医学院_眼科_期刊论文

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作者单位: 1.China Med Univ, Affiliated Hosp 1, Dept Ophthalmol, Shenyang 110001, Peoples R China
2.Mudanjiang Med Coll, Mudanjiang, Peoples R China
3.Peking Univ, Hosp 3, Ctr Eye, Beijing 100871, Peoples R China

Recommended Citation:
Sun, Zhaoyi,Hong, Jing,Liu, Zaiying,et al. Coal Dust Contiguity-induced Changes in the Concentration of TNF- and NF- B p65 on the Ocular Surface[J]. OCULAR IMMUNOLOGY AND INFLAMMATION,2009,17(2):76-82.
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