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学科主题临床医学
Ketamine-Associated Urinary Tract Dysfunction: An Underrecognized Clinical Entity
Lai, Yongqing1,2; Wua, Song1,2; Ni, Liangchao1,2; Chen, Zebo1,2; Li, Xianxin1,2; Yang, Shangqi1,2; Gui, Yaoting2; Guan, Zhichen1; Cai, Zhiming1,2; Ye, Jiongxian1,2
关键词Adult Bladder Dysfunction Urinary Bladder Urodynamic Study Voiding Dysfunction Ketamine Bladder Dysfunction
刊名UROLOGIA INTERNATIONALIS
2012
DOI10.1159/000338098
89期:1页:93-96
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Urology & Nephrology
资助者National Natural Science Foundation of China ; National Natural Science Foundation of China
研究领域[WOS]Urology & Nephrology
关键词[WOS]BLADDER DYSFUNCTION ; CYSTITIS
英文摘要

Introduction: The use of ketamine as a recreational drug is on the increase among young adults attending clubs and parties. Recreational ketamine users have anecdotally reported increased lower urinary tract symptoms while using the substance. Methods: We describe the severe lower urinary tract symptoms experienced in 6 patients with chronic recreational ketannine use. We obtained a detailed history and physical examination along with further investigation to identify a relationship between recreational ketamine use and these symptoms. Results:The urine cultures were sterile in all cases. Intravenous urography was performed in 3 patients and demonstrated bilateral upper ureteric narrow, mild bilateral hydronephrosis and contracted bladder urodynamic studies showed detrusor instability with urinary leakage when the bladder was filled to a capacity of 30-50 ml. Cystoscopy revealed a small capacity bladder with erythematous lesions throughout the bladder. Bladder biopsies were performed in 3 patients and showed up as chronic cystitis. Ketamine cessation along with intravesical sodium hyaluronate solution appeared to provide some symptomatic relief. Conclusion: Ketamine-associated urinary tract dysfunction appears to be a relatively new clinical phenomenon. The pathological mechanism of ketamine-associated urinary tract dysfunction is unknown and current management strategies are ketamine cessation along with intravesical sodium hyaluronate solution. Copyright (C) 2012 S. Karger AG, Basel

语种英语
所属项目编号81101922
资助者National Natural Science Foundation of China ; National Natural Science Foundation of China
WOS记录号WOS:000306888100016
引用统计
被引频次:16[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/53252
专题北京大学深圳医院_泌尿外科
作者单位1.Peking Univ, Shenzhen Hosp, Dept Urol, Shenzhen PKU HKUST Med Ctr,Inst Urol, Shenzhen 518036, Peoples R China
2.Peking Univ, Shenzhen Hosp, Key Lab Stem Cell Biol,Guangdon & Shenzhen Key La, Shenzhen PKU HKUST Med Ctr,Inst Urol, Shenzhen 518036, Peoples R China
推荐引用方式
GB/T 7714
Lai, Yongqing,Wua, Song,Ni, Liangchao,et al. Ketamine-Associated Urinary Tract Dysfunction: An Underrecognized Clinical Entity[J]. UROLOGIA INTERNATIONALIS,2012,89(1):93-96.
APA Lai, Yongqing.,Wua, Song.,Ni, Liangchao.,Chen, Zebo.,Li, Xianxin.,...&Ye, Jiongxian.(2012).Ketamine-Associated Urinary Tract Dysfunction: An Underrecognized Clinical Entity.UROLOGIA INTERNATIONALIS,89(1),93-96.
MLA Lai, Yongqing,et al."Ketamine-Associated Urinary Tract Dysfunction: An Underrecognized Clinical Entity".UROLOGIA INTERNATIONALIS 89.1(2012):93-96.
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