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学科主题: 基础医学
题名:
Thiazolidinediones: A novel class of drugs for the prevention of diabetic nephropathy?
作者: Zheng, F.1; Guan, Y.1
刊名: KIDNEY INTERNATIONAL
发表日期: 2007-12-01
DOI: 10.1038/sj.ki.5002557
卷: 72, 期:11, 页:1301-1303
收录类别: SCI
文章类型: Editorial Material
WOS标题词: Science & Technology
类目[WOS]: Urology & Nephrology
研究领域[WOS]: Urology & Nephrology
关键词[WOS]: MECHANISMS ; DISEASE ; KIDNEY
英文摘要:

Diabetic nephropathy is the leading cause of end-stage renal disease. Novel preventive measures for diabetic renal complications are urgently needed. Miyazaki et al. report that rosiglitazone, a thiazolidinedione insulin sensitizer and a potent peroxisome proliferator-activated receptor. agonist, not only effectively improves glycemic control but also halts progression of albuminuria in type 2 diabetic patients with early-stage diabetic nephropathy. These findings could offer a new prevention of diabetic nephropathy in insulin-resistant diabetic patients.

语种: 英语
WOS记录号: WOS:000250955900002
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/53294
Appears in Collections:基础医学院_北京大学糖尿病中心_期刊论文

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作者单位: 1.Mt Sinai Hosp, Div Expt Diabet & Aging, New York, NY USA
2.Vanderbilt Univ, Med Ctr, Div Nephrol, Nashville, TN USA
3.Peking Univ, Ctr Diabet, Hlth Sci Ctr, Dept Physiol & Pathophysiol, Beijing 100083, Peoples R China

Recommended Citation:
Zheng, F.,Guan, Y.. Thiazolidinediones: A novel class of drugs for the prevention of diabetic nephropathy?[J]. KIDNEY INTERNATIONAL,2007,72(11):1301-1303.
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