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学科主题: 临床医学
题名:
Intralesional Excision versus Wide Resection for Giant Cell Tumor Involving the Acetabulum: Which is Better?
作者: Guo, Wei; Sun, Xin; Zang, Jie; Qu, Huayi
刊名: CLINICAL ORTHOPAEDICS AND RELATED RESEARCH
发表日期: 2012-04-01
DOI: 10.1007/s11999-011-2190-6
卷: 470, 期:4, 页:1213-1220
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Orthopedics ; Surgery
研究领域[WOS]: Orthopedics ; Surgery
关键词[WOS]: TERM-FOLLOW-UP ; SURGICAL-TREATMENT ; RADIATION-THERAPY ; MALIGNANT-TUMORS ; LOCAL RECURRENCE ; BONE ; RECONSTRUCTION ; PELVIS ; COMPLICATIONS ; MANAGEMENT
英文摘要:

Because of the anatomic complexity of the pelvis, there is no standard surgical treatment for giant cell tumors (GCTs) of the pelvic bones, especially in the periacetabular region. Treatment options include intralesional curettage with or without adjunctive techniques and wide resection. The best surgical treatment of a pelvic GCT remains controversial.

We compared wide resection and intralesional excision in terms of (1) local control, (2) function, and (3) complications.

We retrospectively identified 27 patients with periacetabular benign GCTs who underwent surgery from July 1999 to July 2009. Intralesional surgery was performed in 13 patients and wide resection in 14 patients. We determined surgical complications, local disease control, and Musculoskeletal Tumor Society (MSTS) 93 functional score. The minimum followup was 18 months (mean, 50 months; range, 18-121 months).

Four of 13 patients who had intralesional surgery and none of 14 who had wide resection had local recurrence. The mean functional score was 24 for the 13 patients who underwent intralesional surgery and 22 for the 14 patients who had wide resection. One minor and one major complication occurred among patients who underwent intralesional surgery and one minor and six major complications occurred among patients who underwent wide resection.

Even with a higher complication rate with wide resection and prosthetic reconstruction, we believe the lower local recurrence rate makes wide resection a reasonable option for patients with extensive and/or aggressive GCTs involving the acetabulum.

Level IV, therapeutic study. See Guidelines for Authors for a complete description of levels of evidence.

语种: 英语
WOS记录号: WOS:000301442800033
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/53336
Appears in Collections:北京大学第二临床医学院_骨肿瘤科_期刊论文

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作者单位: Peking Univ, Peoples Hosp, Musculoskeletal Tumor Ctr, Beijing 100044, Peoples R China

Recommended Citation:
Guo, Wei,Sun, Xin,Zang, Jie,et al. Intralesional Excision versus Wide Resection for Giant Cell Tumor Involving the Acetabulum: Which is Better?[J]. CLINICAL ORTHOPAEDICS AND RELATED RESEARCH,2012,470(4):1213-1220.
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