IR@PKUHSC  > 北京大学基础医学院  > 生物物理学系
学科主题基础医学
The measurement of shear modulus and membrane surface viscosity of RBC membrane with Ektacytometry: A new technique
Lu, Xiao1; Tang, Zhi-yu1; Zeng, Zhu1; Chen, Xi1; Yao, Wei-juan1; Yan, Zong-yi1; Shi, Yan1; Shan, Hui-xian1; Sun, Da-gong1; He, Dong-qi1; Wen, Zong-yao1
关键词RBC membrane shear modulus membrane surface viscosity ektacytometry flow chamber
刊名MATHEMATICAL BIOSCIENCES
2007-09-01
DOI10.1016/j.mbs.2006.09.026
209期:1页:190-204
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Biology ; Mathematical & Computational Biology
研究领域[WOS]Life Sciences & Biomedicine - Other Topics ; Mathematical & Computational Biology
关键词[WOS]RED-BLOOD-CELL ; FLOW FIELD ; HUMAN ERYTHROCYTE ; ORIENTATION ; DEFORMATION ; DEFORMABILITY ; ELASTICITY
英文摘要

A new technique is proposed to estimate the shear modulus (p) and membrane surface viscosity (eta(m)) of red blood cell (RBC). Theoretical formulae for finding these two parameters are first derived based on the force balance on a RBC in a flow field of low viscosity. Different types of Ektacytometry are then used to measure relevant quantities. The obtained values (mu = 6.1 x 10(-6) N/m, eta(m) = 8.8 X 10(-7) N s/m for normal RBC) are consistent with those previously found by micropipette technique and in AC electric field. The present technique is, however, much easier to operate and more advantageous in reflecting the average properties of a large quantity of RBCs, and it is much cheaper to be applied in clinical practice than any other method of measuring the two parameters. The sensitivity of the technique is demonstrated by

语种英语
WOS记录号WOS:000249511300010
引用统计
被引频次:2[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
版本出版稿
条目标识符http://ir.bjmu.edu.cn/handle/400002259/53342
专题北京大学基础医学院_生物物理学系
作者单位1.Chengde Med Coll, Dept Math, Chengde 067000, Peoples R China
2.Beijing Univ, Dept Math, Beijing 100083, Peoples R China
3.Peking Univ, Hlth Sci Ctr, Dept Biophys, Beijing 100083, Peoples R China
4.Peking Univ, Dept Mech & Engn Sci, Beijing 100871, Peoples R China
5.Peking Univ, Hlth Sci Ctr, Dept Appl Sci, Beijing 100083, Peoples R China
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GB/T 7714
Lu, Xiao,Tang, Zhi-yu,Zeng, Zhu,et al. The measurement of shear modulus and membrane surface viscosity of RBC membrane with Ektacytometry: A new technique[J]. MATHEMATICAL BIOSCIENCES,2007,209(1):190-204.
APA Lu, Xiao.,Tang, Zhi-yu.,Zeng, Zhu.,Chen, Xi.,Yao, Wei-juan.,...&Wen, Zong-yao.(2007).The measurement of shear modulus and membrane surface viscosity of RBC membrane with Ektacytometry: A new technique.MATHEMATICAL BIOSCIENCES,209(1),190-204.
MLA Lu, Xiao,et al."The measurement of shear modulus and membrane surface viscosity of RBC membrane with Ektacytometry: A new technique".MATHEMATICAL BIOSCIENCES 209.1(2007):190-204.
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