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Perinatal and background risk factors for childhood autism in central China
Duan, Guiqin2; Yao, Meiling2; Ma, Yating1; Zhang, Wenjing3
关键词Childhood Autism Central China Perinatal Risk Factors
刊名PSYCHIATRY RESEARCH
2014-12-15
DOI10.1016/j.psychres.2014.05.057
220期:1-2页:410-417
收录类别SCI ; SSCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Psychiatry
研究领域[WOS]Psychiatry
关键词[WOS]LOW-BIRTH-WEIGHT ; SPECTRUM DISORDERS ; INFANTILE-AUTISM ; NEONATAL JAUNDICE ; MATERNAL SMOKING ; FAMILY-HISTORY ; PATERNAL AGE ; DIAGNOSIS ; CHILDREN ; ETIOLOGY
英文摘要

Perinatal and background risk factors for autism were identified in a cohort of autistic children in Zhengzhou, China, to formulate preventative and treatment strategies for high-risk families. In this case-control study, children were screened for suspected autism using the Autism Behavior Checklist (ABC) and diagnosed according to DSM-IV and the Childhood Autism Rating Scale (CARS). We collected perinatal histories and clinical data of 286 confirmed autistic children treated at the Third Affiliated Hospital Children′s Psychological Clinic of Zhengzhou University from 2011 to 2013. The control group consisted of 286 healthy children from area kindergartens. Maternal age > 30 years, parental introversion as measured by the Eysenck Personality Questionnaire, low level of parental education, smoking, abortion threat, pregnancy complications, maternal illness during pregnancy, maternal mental health, family history of mental illness, neonatal jaundice, birth asphyxia, premature rupture of the fetal membrane, and gestational age < 37 weeks were significantly higher in the autism group. These factors were significantly correlated with behavioral symptoms as measured by ABC scores (Kendall rank correlation). Birth asphyxia, neonatal jaundice, maternal age, parental introversion, family history of mental illness, abortion threat, premature delivery, and smoking were identified as independent risk factors by multivariate logistic regression. (C) 2014 Elsevier Ireland Ltd. All rights reserved.

语种英语
WOS记录号WOS:000345058400064
Citation statistics
Cited Times:10[WOS]   [WOS Record]     [Related Records in WOS]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/53440
Collection北京大学公共卫生学院
作者单位1.Peking Univ, Inst Child & Adolescent Hlth, Sch Publ Hlth, Hlth Sci Ctr, Beijing 100191, Peoples R China
2.Zhengzhou Univ, Affiliated Hosp 3, Ctr Children Psychol & Behav, Zhengzhou 450052, Henan Province, Peoples R China
3.Beijing Acad Educ Sci, Beijing 100045, Peoples R China
Recommended Citation
GB/T 7714
Duan, Guiqin,Yao, Meiling,Ma, Yating,et al. Perinatal and background risk factors for childhood autism in central China[J]. PSYCHIATRY RESEARCH,2014,220(1-2):410-417.
APA Duan, Guiqin,Yao, Meiling,Ma, Yating,&Zhang, Wenjing.(2014).Perinatal and background risk factors for childhood autism in central China.PSYCHIATRY RESEARCH,220(1-2),410-417.
MLA Duan, Guiqin,et al."Perinatal and background risk factors for childhood autism in central China".PSYCHIATRY RESEARCH 220.1-2(2014):410-417.
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