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学科主题: 临床医学
题名:
The Relationship between Particulate Matter (PM10) and Hospitalizations and Mortality Of Chronic Obstructive Pulmonary Disease: A Meta-Analysis
作者: Zhu, Ruixia1; Chen, Yahong1; Wu, Shaowei2; Deng, Furong2; Liu, Yue2; Yao, Wanzhen1
关键词: Particulate matter ; COPD ; hospitalizations mortality ; meta-analysis
刊名: COPD-JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE
发表日期: 2013-06-01
DOI: 10.3109/15412555.2012.744962
卷: 10, 期:3, 页:307-315
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Respiratory System
研究领域[WOS]: Respiratory System
关键词[WOS]: EMERGENCY-DEPARTMENT VISITS ; CASE-CROSSOVER ANALYSIS ; SHORT-TERM ASSOCIATION ; AMBIENT AIR-POLLUTION ; TIME-SERIES ; RESPIRATORY-DISEASES ; AIRBORNE PARTICLES ; EFFECT MODIFIERS ; HONG-KONG ; ADMISSIONS
英文摘要:

Background: Numerous studies have reported variable associations between ambient particulate matter (PM) and chronic obstructive pulmonary disease (COPD) hospitalizations and mortality. Objective: To conduct a systematic study assessing the associations between hospitalizations and mortality from COPD and ambient PM10 (particulate matter with aerodynamic diameters <= 10 mu m, PM10). Methods: Systematic searches were conducted in 6 common electronic databases. A meta-analysis was performed to estimate the odds ratio (OR) to evaluate the relationship between PM10 and COPD hospitalizations and mortality. Publication bias and heterogeneity of samples were tested by Begg funnel plot and Egger test, respectively. Study fi ndings were analyzed using random-effect model and fi xedeffect model. Results: The search yielded 31 studies suitable for the meta-analysis during the period from Jan 1, 2000 to Oct 31, 2011. A 10 mu g/m(3) increase in PM10 was associated with a 2.7% (95% CI = 1.9%-3.6%) increase in COPD hospitalizations with an OR of 1.027 (95% CI: 1.019-1.036), and a 1.1% (95% CI: 0.8%-1.4%) increase in COPD mortality with an OR of 1.011 (95% CI: 1.008-1.014). Conclusions: Ambient PM10 is associated with increased COPD hospitalizations and mortality. Further research is needed to elucidate whether this association is causal and to clarify its mechanisms.

语种: 英语
所属项目编号: 81072267 ; 81170012
项目资助者: National Natural Science Foundation of China
WOS记录号: WOS:000319526000006
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/53484
Appears in Collections:北京大学第三临床医学院_呼吸内科_期刊论文

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作者单位: 1.Peking Univ, Hosp 3, Resp Dept, Beijing 100871, Peoples R China
2.Peking Univ, Sch Publ Hlth, Dept Occupat & Environm Hlth Sci, Beijing 100871, Peoples R China

Recommended Citation:
Zhu, Ruixia,Chen, Yahong,Wu, Shaowei,et al. The Relationship between Particulate Matter (PM10) and Hospitalizations and Mortality Of Chronic Obstructive Pulmonary Disease: A Meta-Analysis[J]. COPD-JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE,2013,10(3):307-315.
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