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The Relationship between Particulate Matter (PM10) and Hospitalizations and Mortality Of Chronic Obstructive Pulmonary Disease: A Meta-Analysis
Zhu, Ruixia1; Chen, Yahong1; Wu, Shaowei2; Deng, Furong2; Liu, Yue2; Yao, Wanzhen1
关键词Particulate Matter Copd Hospitalizations Mortality Meta-analysis
刊名COPD-JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE
2013-06-01
DOI10.3109/15412555.2012.744962
10期:3页:307-315
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Respiratory System
研究领域[WOS]Respiratory System
关键词[WOS]EMERGENCY-DEPARTMENT VISITS ; CASE-CROSSOVER ANALYSIS ; SHORT-TERM ASSOCIATION ; AMBIENT AIR-POLLUTION ; TIME-SERIES ; RESPIRATORY-DISEASES ; AIRBORNE PARTICLES ; EFFECT MODIFIERS ; HONG-KONG ; ADMISSIONS
英文摘要

Background: Numerous studies have reported variable associations between ambient particulate matter (PM) and chronic obstructive pulmonary disease (COPD) hospitalizations and mortality. Objective: To conduct a systematic study assessing the associations between hospitalizations and mortality from COPD and ambient PM10 (particulate matter with aerodynamic diameters <= 10 mu m, PM10). Methods: Systematic searches were conducted in 6 common electronic databases. A meta-analysis was performed to estimate the odds ratio (OR) to evaluate the relationship between PM10 and COPD hospitalizations and mortality. Publication bias and heterogeneity of samples were tested by Begg funnel plot and Egger test, respectively. Study fi ndings were analyzed using random-effect model and fi xedeffect model. Results: The search yielded 31 studies suitable for the meta-analysis during the period from Jan 1, 2000 to Oct 31, 2011. A 10 mu g/m(3) increase in PM10 was associated with a 2.7% (95% CI = 1.9%-3.6%) increase in COPD hospitalizations with an OR of 1.027 (95% CI: 1.019-1.036), and a 1.1% (95% CI: 0.8%-1.4%) increase in COPD mortality with an OR of 1.011 (95% CI: 1.008-1.014). Conclusions: Ambient PM10 is associated with increased COPD hospitalizations and mortality. Further research is needed to elucidate whether this association is causal and to clarify its mechanisms.

语种英语
WOS记录号WOS:000319526000006
引用统计
被引频次:14[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/53484
专题北京大学第三临床医学院_呼吸科
北京大学公共卫生学院_劳动卫生与环境卫生学系
北京大学第三临床医学院_运动医学研究所
作者单位1.Peking Univ, Hosp 3, Resp Dept, Beijing 100871, Peoples R China
2.Peking Univ, Sch Publ Hlth, Dept Occupat & Environm Hlth Sci, Beijing 100871, Peoples R China
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GB/T 7714
Zhu, Ruixia,Chen, Yahong,Wu, Shaowei,et al. The Relationship between Particulate Matter (PM10) and Hospitalizations and Mortality Of Chronic Obstructive Pulmonary Disease: A Meta-Analysis[J]. COPD-JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE,2013,10(3):307-315.
APA Zhu, Ruixia,Chen, Yahong,Wu, Shaowei,Deng, Furong,Liu, Yue,&Yao, Wanzhen.(2013).The Relationship between Particulate Matter (PM10) and Hospitalizations and Mortality Of Chronic Obstructive Pulmonary Disease: A Meta-Analysis.COPD-JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE,10(3),307-315.
MLA Zhu, Ruixia,et al."The Relationship between Particulate Matter (PM10) and Hospitalizations and Mortality Of Chronic Obstructive Pulmonary Disease: A Meta-Analysis".COPD-JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE 10.3(2013):307-315.
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