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学科主题: 临床医学
题名:
Prevalence of Unrecognized Lower Extremity Peripheral Arterial Disease and the Associated Factors in Chinese Hypertensive Adults
作者: He, Mingli2; Qin, Xianhui3; Cui, Yimin4; Cai, Yefeng5; Sun, Liming6; Xu, Xin1; Wang, Binyan3; Tang, Genfu7; Xing, Houxun8; Wang, Xiaobin9; Xu, Xiping1; Huo, Yong10
刊名: AMERICAN JOURNAL OF CARDIOLOGY
发表日期: 2012-12-01
DOI: 10.1016/j.amjcard.2012.07.038
卷: 110, 期:11, 页:1692-1698
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Cardiac & Cardiovascular Systems
研究领域[WOS]: Cardiovascular System & Cardiology
关键词[WOS]: HEART-RATE ; CARDIOVASCULAR-DISEASE ; TASK-FORCE ; PRACTICE GUIDELINES ; EUROPEAN-SOCIETY ; SLEEP DURATION ; MANAGEMENT ; MORTALITY ; WOMEN ; RISK
英文摘要:

We aimed to examine the prevalence of lower-extremity peripheral artery disease (LE-PAD) and its associated factors in 3,128 Chinese hypertensive adults 45 to 75 years old without known cardiovascular disease, PAD, chronic kidney disease, diabetes, and dyslipidemia. A cross-sectional investigation was carried out in a rural area of Lianyungang, China. An ankle-brachial index <= 0.90 in either leg was used to define LE-PAD. Prevalence of LE-PAD was 9.0% (10.0% in women and 7.4% in men). In the multivariable logistic regression model, odds ratios (95% confidence interval) of having LE-PAD, were 1.82 (1.27 to 2.61) for participants 65 to 75 versus 45 to 55 years old, 1.48 (1.00 to 1.20) for participants with a waist circumference >= 90 versus < 90 cm, 1.47 (1.05 to 2.04) and 1.62 (1.15 to 2.27) for participants with grade 2 and 3 hypertension versus controlled blood pressure or grade 1 hypertension, 1.35 (1.00 to 1.83) and 1.61 (1.16 to 2.23) for participants with heart rate at rest 70 to 80 and >= 80 versus < 70 beats/min, and 1.41 (1.00 to 1.97) for participants with poor versus good sleeping quality. For other risk factors, gender-related differences were observed. Adjusted odds ratios of having LE-PAD for men and women were 1.07 (0.66 to 1.74) and 0.65 (0.47 to 0.90) for inland versus coastal residents and 1.03 (0.57 to 1.86) and 1.62 (1.09 to 2.41) for participants with body mass index >= 25 versus < 25 kg/m(2). In conclusion, there was a high prevalence of LE-PAD in Chinese hypertensive adults without known cardiovascular disease, PAD, chronic kidney disease, diabetes, and dyslipidemia, particularly in women in coastal areas and in participants with higher heart rate and poor sleeping quality. Therefore, ankle-brachial index determinations should be encouraged in clinical practice in Chinese hypertensive adults. (c) 2012 Elsevier Inc. All rights reserved. (Am J Cardiol 2012;110:1692-1698)

语种: 英语
所属项目编号: 2012zx09101-105 ; 2012CB517703 ; (2010)1744
项目资助者: Ministry of Science and Technology of the People&prime ; s Republic of China ; Major State Basic Research Development Program of China (973 program) ; Department of Development and Reform, Shenzhen, Guangdong, China ; Department of Science, industry, Trade and Information Technology, Shenzhen, Guangdong, China
WOS记录号: WOS:000311868000023
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/53491
Appears in Collections:北京大学第一临床医学院_药剂科_期刊论文

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作者单位: 1.Second Hosp Lianyungang City, Dept Cardiol, Lianyungang, Peoples R China
2.Anhui Med Univ, Sch Hlth Adm, Hefei, Peoples R China
3.Lianyungang Ctr Adv Res Cardiovasc Dis, Lianyungang, Peoples R China
4.Anhui Med Univ, Inst Biomed, Hefei, Peoples R China
5.Peking Univ, Dept Pharm, Hosp 1, Beijing 100871, Peoples R China
6.So Med Univ, Inst Nephrol, Guangzhou, Guangdong, Peoples R China
7.First Peoples Hosp Lianyungang City, Dept Neurol, Lianyungang, Peoples R China
8.Guangdong Tradit Chinese Med Hosp, Dept Neurol, Guangzhou, Guangdong, Peoples R China
9.Johns Hopkins Univ, Bloomberg Sch Publ Hlth, Ctr Early Life Origins Dis, Dept Populat Family & Reprod Hlth, Baltimore, MD USA
10.Peking Univ, Dept Cardiol, Hosp 1, Beijing 100871, Peoples R China

Recommended Citation:
He, Mingli,Qin, Xianhui,Cui, Yimin,et al. Prevalence of Unrecognized Lower Extremity Peripheral Arterial Disease and the Associated Factors in Chinese Hypertensive Adults[J]. AMERICAN JOURNAL OF CARDIOLOGY,2012,110(11):1692-1698.
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