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IR@PKUHSC  > 北京大学第三临床医学院  > 泌尿外科  > 期刊论文
学科主题: 临床医学
题名:
Efficacy and Safety of 120-W Thulium:Yttrium-Aluminum-Garnet Vapoenucleation of Prostates Compared with Holmium Laser Enucleation of Prostates for Benign Prostatic Hyperplasia
作者: Hong, Kai; Liu, Yu-Qing; Lu, Jian; Xiao, Chun-Lei; Huang, Yi; Ma, Lu-Lin
关键词: Benign Prostatic Hyperplasia ; Holmium Lasers ; Laser Surgery ; Prostatectomy ; Thulium ; Transurethral
刊名: CHINESE MEDICAL JOURNAL
发表日期: 2015-04-05
DOI: 10.4103/0366-6999.154282
卷: 128, 期:7, 页:884-889
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Medicine, General & Internal
研究领域[WOS]: General & Internal Medicine
关键词[WOS]: CONTINUOUS-WAVE LASER ; 12-MONTH FOLLOW-UP ; TRANSURETHRAL RESECTION ; THULIUM/YAG VAPOENUCLEATION ; THUVEP ; BPH
英文摘要:

Background: This study compared the efficacy and safety between 120-W thulium: yttrium-aluminum-garnet (Tm:YAG) vapoenucleation of prostates (ThuVEP) and holmium laser enucleation of prostates (HoLEP) for patients with lower urinary tract symptoms (LUTS) due to benign prostatic hyperplasia (BPH).

Methods: A retrospective analysis of 88 consecutive patients with symptomatic BPH was carried out, who underwent either 120-W ThuVEP or HoLEP nonrandomly. Patient demographics and peri-operative and 12-month follow-up data were analyzed with the International Prostate Symptom Score (IPSS), quality of life (QoL) score, maximum flow rate (Qmax), postvoid residual urine volume (PVR), and rates of peri-operative and late complications.

Results: The patients in each group showed no significant difference in preoperative parameters. Compared with the HoLEP group, patients in the 120-W ThuVEP group required significantly shorter time for laser enucleation (58.3 +/- 12.8 min vs. 70.5 +/- 22.3 min, P = 0.003), and resulted in a significant superiority in laser efficiency (resected prostate weight/laser enucleation time) for 120-W Tm: YAG laser compared to holmium: YAG laser (0.69 +/- 0.18 vs. 0.61 +/- 0.19, P = 0.048). During 1, 6, and 12 months of follow-ups, the procedures did not demonstrate a significant difference in IPSS, QoL score, Qmax, or PVR (P > 0.05). Mean peri-operative decrease of hemoglobin in the HoLEP group was similar to the ThuVEP group (17.1 +/- 12.0 g/L vs. 15.2 +/- 10.1 g/L, P = 0.415). Early and late incidences of complications were low and did not differ significantly between the two groups of 120-W ThuVEP and HoLEP patients (P > 0.05).

Conclusions: 120-W ThuVEP and HoLEP are potent, safe and efficient modalities of minimally invasive surgeries for patients with LUTS due to BPH. Compared with HoLEP, 120-W ThuVEP offers advantages of reduction of laser enucleation time and improvement of laser efficiency.

语种: 英语
所属项目编号: Z141100002114027
项目资助者: Beijing Municipal Science &amp ; Technology Commission
WOS记录号: WOS:000352533500006
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/53540
Appears in Collections:北京大学第三临床医学院_泌尿外科_期刊论文

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作者单位: Peking Univ, Hosp 3, Dept Urol, Beijing 100191, Peoples R China

Recommended Citation:
Hong, Kai,Liu, Yu-Qing,Lu, Jian,et al. Efficacy and Safety of 120-W Thulium:Yttrium-Aluminum-Garnet Vapoenucleation of Prostates Compared with Holmium Laser Enucleation of Prostates for Benign Prostatic Hyperplasia[J]. CHINESE MEDICAL JOURNAL,2015,128(7):884-889.
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