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IR@PKUHSC  > 北京大学第三临床医学院  > 心血管内科  > 期刊论文
学科主题: 临床医学
题名:
Design and synthesis of novel aryloxyalkyl-arylpiperazine derivatives as alpha(1A)-adrenoceptor antagonists
作者: Fang, H; Li, MY; Xia, L; Jiang, ZZ; Lu, ZZ
关键词: alpha(1)-Adrenoceptor ; antagonist ; aryloxyalkyl-arylpiperazine
刊名: CHINESE CHEMICAL LETTERS
发表日期: 2005-04-01
卷: 16, 期:4, 页:445-448
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Chemistry, Multidisciplinary
研究领域[WOS]: Chemistry
关键词[WOS]: BENIGN PROSTATIC HYPERPLASIA
英文摘要:

A series of 1-[2-(substituted phenoxy)ethyl]-4-(2-methoxyphenyl)-piperazine derivatives have been synthesized. The radioligand receptor binding assay indicated that most of them bind with alpha(1)-adrenoceptor specifically, and one of the compound possessed subtype A selectivity.

语种: 英语
WOS记录号: WOS:000228574100007
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/53612
Appears in Collections:北京大学第三临床医学院_心血管内科_期刊论文

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作者单位: 1.Shandong Univ, Dept Med Chem, Jinan 250012, Peoples R China
2.China Pharmaceut Univ, Xinzhong New Drug Screening Ctr, Nanjing 210038, Peoples R China
3.Peking Univ, Hosp 3, Inst Vasc Med, Beijing 100083, Peoples R China

Recommended Citation:
Fang, H,Li, MY,Xia, L,et al. Design and synthesis of novel aryloxyalkyl-arylpiperazine derivatives as alpha(1A)-adrenoceptor antagonists[J]. CHINESE CHEMICAL LETTERS,2005,16(4):445-448.
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