|Prospective observational study of acute coronary syndromes in China: practice patterns and outcomes|
|Gao, R.1; Patel, A.2; Gao, W.3; Hu, D.4; Huang, D.5; Kong, L.6; Qi, W.7; Wu, Y.8; Yang, Y.1; Harris, P.9; Algert, C.2; Groenestein, P.2; Turnbull, F.2; CPACS Investigators|
|WOS标题词||Science & Technology|
|类目[WOS]||Cardiac & Cardiovascular Systems|
|研究领域[WOS]||Cardiovascular System & Cardiology|
|关键词[WOS]||ACUTE MYOCARDIAL-INFARCTION ; PLACEBO-CONTROLLED TRIAL ; ACUTE ISCHEMIC SYNDROMES ; GLOBAL REGISTRY ; EVENTS GRACE ; RISK STRATIFICATION ; RANDOMIZED-TRIAL ; ARTERY-DISEASE ; ST ELEVATION ; PRAIS-UK|
Objective: To describe the investigation and management of patients admitted to hospitals in China with suspected acute coronary syndromes (ACS) and to identify potential areas for improvement in practice.
Design: A multicentre prospective survey of socio-demographic characteristics, medical history, clinical features, in-hospital investigations, treatment practices and major events among patients with suspected ACS.
Setting: Large urban public hospitals.
Patients: Consecutive patients admitted to in-patient facilities with a diagnosis of suspected acute myocardial infarction (MI) or unstable angina pectoris.
Main outcome measures: Myocardial infarction/reinfarction, heart failure, death.
Results: Between September 2004 and May 2005, data were collected prospectively from 2973 patients admitted to 51 hospitals in 18 provinces of China. An initial diagnosis of ST elevation MI, non-ST elevation MI and unstable angina was made in 43%, 11% and 46% of patients, respectively. Diagnosis was inconsistent with objective measures in up to 20% of cases. At both tertiary and non-tertiary centres, there was little evidence that clinical risk stratification was used to determine the intensity of investigation and management. The mortality rate during hospitalisation was 5% overall and similar in tertiary and non-tertiary centres, but reported in-hospital re-infarction rates (8%) and heart failure rates (16%) were substantially higher at non-tertiary centres.
Conclusion: This study has identified a number of areas in the management of ACS patients, including diagnosis and risk stratification, which deviate from current guidelines. These findings will help inform the introduction of widely used quality improvement initiatives such as clinical pathways.
|作者单位||1.W China Hosp, Sichuan, Peoples R China|
2.Royal Prince Alfred Hosp, Sydney, NSW, Australia
3.Minist Hlth, Dept Dis Control & Prevent, Beijing, Peoples R China
4.Ruijin Hosp, Shanghai, Peoples R China
5.George Inst Int Hlth, Beijing, Peoples R China
6.Univ Sydney, George Inst Int Hlth, Sydney, NSW 2050, Australia
7.Peking Univ, Hosp 3, Beijing 100871, Peoples R China
8.Peking Univ, Peoples Hosp, Beijing 100871, Peoples R China
9.FuWai Heart Hosp, Beijing, Peoples R China
|Gao, R.,Patel, A.,Gao, W.,et al. Prospective observational study of acute coronary syndromes in China: practice patterns and outcomes[J]. HEART,2008,94(5):554-560.|
|APA||Gao, R..,Patel, A..,Gao, W..,Hu, D..,Huang, D..,...&CPACS Investigators.(2008).Prospective observational study of acute coronary syndromes in China: practice patterns and outcomes.HEART,94(5),554-560.|
|MLA||Gao, R.,et al."Prospective observational study of acute coronary syndromes in China: practice patterns and outcomes".HEART 94.5(2008):554-560.|