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学科主题: 临床医学
题名:
Prospective observational study of acute coronary syndromes in China: practice patterns and outcomes
作者: Gao, R.1; Patel, A.2; Gao, W.3; Hu, D.4; Huang, D.5; Kong, L.6; Qi, W.7; Wu, Y.8; Yang, Y.1; Harris, P.9; Algert, C.2; Groenestein, P.2; Turnbull, F.2; CPACS Investigators
刊名: HEART
发表日期: 2008-05-01
DOI: 10.1136/hrt.2007.119750
卷: 94, 期:5, 页:554-560
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Cardiac & Cardiovascular Systems
研究领域[WOS]: Cardiovascular System & Cardiology
关键词[WOS]: ACUTE MYOCARDIAL-INFARCTION ; PLACEBO-CONTROLLED TRIAL ; ACUTE ISCHEMIC SYNDROMES ; GLOBAL REGISTRY ; EVENTS GRACE ; RISK STRATIFICATION ; RANDOMIZED-TRIAL ; ARTERY-DISEASE ; ST ELEVATION ; PRAIS-UK
英文摘要:

Objective: To describe the investigation and management of patients admitted to hospitals in China with suspected acute coronary syndromes (ACS) and to identify potential areas for improvement in practice.

Design: A multicentre prospective survey of socio-demographic characteristics, medical history, clinical features, in-hospital investigations, treatment practices and major events among patients with suspected ACS.

Setting: Large urban public hospitals.

Patients: Consecutive patients admitted to in-patient facilities with a diagnosis of suspected acute myocardial infarction (MI) or unstable angina pectoris.

Main outcome measures: Myocardial infarction/reinfarction, heart failure, death.

Results: Between September 2004 and May 2005, data were collected prospectively from 2973 patients admitted to 51 hospitals in 18 provinces of China. An initial diagnosis of ST elevation MI, non-ST elevation MI and unstable angina was made in 43%, 11% and 46% of patients, respectively. Diagnosis was inconsistent with objective measures in up to 20% of cases. At both tertiary and non-tertiary centres, there was little evidence that clinical risk stratification was used to determine the intensity of investigation and management. The mortality rate during hospitalisation was 5% overall and similar in tertiary and non-tertiary centres, but reported in-hospital re-infarction rates (8%) and heart failure rates (16%) were substantially higher at non-tertiary centres.

Conclusion: This study has identified a number of areas in the management of ACS patients, including diagnosis and risk stratification, which deviate from current guidelines. These findings will help inform the introduction of widely used quality improvement initiatives such as clinical pathways.

语种: 英语
WOS记录号: WOS:000254969300009
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/53677
Appears in Collections:北京大学第三临床医学院_期刊论文

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作者单位: 1.W China Hosp, Sichuan, Peoples R China
2.Royal Prince Alfred Hosp, Sydney, NSW, Australia
3.Minist Hlth, Dept Dis Control & Prevent, Beijing, Peoples R China
4.Ruijin Hosp, Shanghai, Peoples R China
5.George Inst Int Hlth, Beijing, Peoples R China
6.Univ Sydney, George Inst Int Hlth, Sydney, NSW 2050, Australia
7.Peking Univ, Hosp 3, Beijing 100871, Peoples R China
8.Peking Univ, Peoples Hosp, Beijing 100871, Peoples R China
9.FuWai Heart Hosp, Beijing, Peoples R China

Recommended Citation:
Gao, R.,Patel, A.,Gao, W.,et al. Prospective observational study of acute coronary syndromes in China: practice patterns and outcomes[J]. HEART,2008,94(5):554-560.
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