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学科主题: 临床医学
题名:
High temporal resolution dynamic contrast-enhanced MRI using compressed sensing-combined sequence in quantitative renal perfusion measurement
作者: Chen, Bin1; Zhao, Kai2; Li, Bo3; Cai, Wenchao2; Wang, Xiaoying1,2; Zhang, Jue1,3; Fang, Jing1,3
关键词: Kidney ; DCE-MRI ; Perfusion ; Compressed sensing ; Temporal resolution
刊名: MAGNETIC RESONANCE IMAGING
发表日期: 2015-10-01
DOI: 10.1016/j.mri.2015.05.004
卷: 33, 期:8, 页:962-969
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Radiology, Nuclear Medicine & Medical Imaging
研究领域[WOS]: Radiology, Nuclear Medicine & Medical Imaging
关键词[WOS]: DCE-MRI ; BREAST ; RECONSTRUCTION ; COMBINATION ; AGENT
英文摘要:

Purpose: To demonstrate the feasibility of the improved temporal resolution by using compressed sensing (CS) combined imaging sequence in dynamic contrast-enhanced MRI (DCE-MRI) of kidney, and investigate its quantitative effects on renal perfusion measurements.

Materials and Methods: Ten rabbits were included in the accelerated scans with a CS-combined 3D pulse sequence. To evaluate the image quality, the signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) were compared between the proposed CS strategy and the conventional full sampling method. Moreover, renal perfusion was estimated by using the separable compartmental model in both CS simulation and realistic CS acquisitions.

Results: The CS method showed DCE-MRI images with improved temporal resolution and acceptable image contrast, while presenting significantly higher SNR than the fully sampled images (p<.01) at 2-, 3- and 4-X acceleration. In quantitative measurements, renal perfusion results were in good agreement with the fully sampled one (concordance correlation coefficient =- 0.95, 0.91, 0.88) at 2-, 3- and 4-X acceleration in CS simulation. Moreover, in realistic acquisitions, the estimated perfusion by the separable compartmental model exhibited no significant differences (p>.05) between each CS-accelerated acquisition and the full sampling method.

Conclusion: The CS-combined 3D sequence could improve the temporal resolution for DCE-MRI in kidney while yielding diagnostically acceptable image quality, and it could provide effective measurements of renal perfusion. (C) 2015 Elsevier Inc. All rights reserved.

语种: 英语
WOS记录号: WOS:000360322600003
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/53698
Appears in Collections:北京大学第一临床医学院_放射治疗科_期刊论文

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作者单位: 1.Peking Univ, Acad Adv Interdisciplinary Studies, Beijing 100871, Peoples R China
2.Peking Univ, Hosp 1, Dept Radiol, Beijing 100034, Peoples R China
3.Peking Univ, Coll Engn, Beijing 100871, Peoples R China

Recommended Citation:
Chen, Bin,Zhao, Kai,Li, Bo,et al. High temporal resolution dynamic contrast-enhanced MRI using compressed sensing-combined sequence in quantitative renal perfusion measurement[J]. MAGNETIC RESONANCE IMAGING,2015,33(8):962-969.
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