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The utility of diffusion-weighted MR imaging in differentiation of uterine adenomyosis and leiomyoma
Qiong, Yang1; Hua, Zhang Li1; Jing, Su2; Liu Jianyu1
关键词Diffusion-weighted Mr Imaging Apparent Diffusion Coefficient Adenomyosis Leiomyoma
刊名EUROPEAN JOURNAL OF RADIOLOGY
2011-08-01
DOI10.1016/j.ejrad.2011.03.026
79期:2页:E47-E51
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Radiology, Nuclear Medicine & Medical Imaging
研究领域[WOS]Radiology, Nuclear Medicine & Medical Imaging
关键词[WOS]CERVICAL-CANCER ; FEATURES
英文摘要

Purpose: To investigate the value of diffusion-weighted MR imaging (DWI), especially apparent diffusion coefficient (ADC) in the differentiation of uterine adenomyosis and leiomyoma.

Materials and methods: 17 patients with uterine leiomyoma and 22 patients with uterine adenomyosis underwent diffusion-weighted imaging (DWI) in addition to routine MR imaging. The ADC values, as well as ADC D-value (defined as the ADC value of high signal intensive foci minus the ADC value of lesion tissues the difference in value), were measured and compared to investigate whether they could help in the differentiation of uterine adenomyosis and leiomyoma. Histopathologic examination was conducted as the golden standard.

Results: For high signal intensive foci within the lesions, uterine adenomyosis demonstrated significantly lower mean ADC value than uterine leiomyoma (1.582 vs. 2.122 x 10(-3) mm(2)/s, P = 0.001). For lesion tissues, uterine adenomyosis demonstrated significantly higher mean ADC value than uterine leiomyoma (1.214 vs. 0.967 x 10(-3) mm(2)/s, P = 0.001). However, there was overlap between uterine adenomyosis and leiomyoma in both measurements. Mean ADC D-value was significantly lower in uterine adenomyosis than in uterine leiomyoma (0.369 vs. 1.096 x 10(-3) mm(2)/s, P = 0.000). ADCD-value had no overlap between uterine adenomyosis and leiomyoma.

Conclusion: DWI can be applied for the further differentiation of uterine adenomyosis and leiomyoma, in addition to routine MR imaging. ADC D-value may be a more useful tool than ADC value in the differentiation. (C) 2011 Elsevier Ireland Ltd. All rights reserved.

语种英语
WOS记录号WOS:000294292700010
引用统计
被引频次:3[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/53712
专题北京大学第三临床医学院_放射科
作者单位1.Peking Univ Third Hosp, Dept Radiol, Beijing 100191, Peoples R China
2.Peking Univ, Hlth Sci Ctr, Dept Pathol, Beijing 100191, Peoples R China
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GB/T 7714
Qiong, Yang,Hua, Zhang Li,Jing, Su,et al. The utility of diffusion-weighted MR imaging in differentiation of uterine adenomyosis and leiomyoma[J]. EUROPEAN JOURNAL OF RADIOLOGY,2011,79(2):E47-E51.
APA Qiong, Yang,Hua, Zhang Li,Jing, Su,&Liu Jianyu.(2011).The utility of diffusion-weighted MR imaging in differentiation of uterine adenomyosis and leiomyoma.EUROPEAN JOURNAL OF RADIOLOGY,79(2),E47-E51.
MLA Qiong, Yang,et al."The utility of diffusion-weighted MR imaging in differentiation of uterine adenomyosis and leiomyoma".EUROPEAN JOURNAL OF RADIOLOGY 79.2(2011):E47-E51.
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