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学科主题: 临床医学
题名:
The utility of diffusion-weighted MR imaging in differentiation of uterine adenomyosis and leiomyoma
作者: Qiong, Yang1; Hua, Zhang Li1; Jing, Su2; Liu Jianyu1
关键词: Diffusion-weighted MR imaging ; Apparent diffusion coefficient ; Adenomyosis ; Leiomyoma
刊名: EUROPEAN JOURNAL OF RADIOLOGY
发表日期: 2011-08-01
DOI: 10.1016/j.ejrad.2011.03.026
卷: 79, 期:2, 页:E47-E51
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Radiology, Nuclear Medicine & Medical Imaging
研究领域[WOS]: Radiology, Nuclear Medicine & Medical Imaging
关键词[WOS]: CERVICAL-CANCER ; FEATURES
英文摘要:

Purpose: To investigate the value of diffusion-weighted MR imaging (DWI), especially apparent diffusion coefficient (ADC) in the differentiation of uterine adenomyosis and leiomyoma.

Materials and methods: 17 patients with uterine leiomyoma and 22 patients with uterine adenomyosis underwent diffusion-weighted imaging (DWI) in addition to routine MR imaging. The ADC values, as well as ADC D-value (defined as the ADC value of high signal intensive foci minus the ADC value of lesion tissues the difference in value), were measured and compared to investigate whether they could help in the differentiation of uterine adenomyosis and leiomyoma. Histopathologic examination was conducted as the golden standard.

Results: For high signal intensive foci within the lesions, uterine adenomyosis demonstrated significantly lower mean ADC value than uterine leiomyoma (1.582 vs. 2.122 x 10(-3) mm(2)/s, P = 0.001). For lesion tissues, uterine adenomyosis demonstrated significantly higher mean ADC value than uterine leiomyoma (1.214 vs. 0.967 x 10(-3) mm(2)/s, P = 0.001). However, there was overlap between uterine adenomyosis and leiomyoma in both measurements. Mean ADC D-value was significantly lower in uterine adenomyosis than in uterine leiomyoma (0.369 vs. 1.096 x 10(-3) mm(2)/s, P = 0.000). ADCD-value had no overlap between uterine adenomyosis and leiomyoma.

Conclusion: DWI can be applied for the further differentiation of uterine adenomyosis and leiomyoma, in addition to routine MR imaging. ADC D-value may be a more useful tool than ADC value in the differentiation. (C) 2011 Elsevier Ireland Ltd. All rights reserved.

语种: 英语
WOS记录号: WOS:000294292700010
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/53712
Appears in Collections:北京大学第三临床医学院_放射科_期刊论文

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作者单位: 1.Peking Univ Third Hosp, Dept Radiol, Beijing 100191, Peoples R China
2.Peking Univ, Hlth Sci Ctr, Dept Pathol, Beijing 100191, Peoples R China

Recommended Citation:
Qiong, Yang,Hua, Zhang Li,Jing, Su,et al. The utility of diffusion-weighted MR imaging in differentiation of uterine adenomyosis and leiomyoma[J]. EUROPEAN JOURNAL OF RADIOLOGY,2011,79(2):E47-E51.
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