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学科主题: 临床医学
题名:
Surgical treatment of liver metastases of colorectal cancer: Strategies and controversies in 2006
作者: Hao, CY; Ji, JF
关键词: colorectal cancer ; liver metastases ; liver resection ; prognosis
刊名: EJSO
发表日期: 2006-06-01
DOI: 10.1016/j.ejso.2006.02.016
卷: 32, 期:5, 页:473-483
收录类别: SCI
文章类型: Review
WOS标题词: Science & Technology
类目[WOS]: Oncology ; Surgery
研究领域[WOS]: Oncology ; Surgery
关键词[WOS]: PORTAL-VEIN EMBOLIZATION ; HEPATIC ARTERIAL INFUSION ; POSITRON-EMISSION-TOMOGRAPHY ; PROGNOSTIC SCORING SYSTEM ; CARCINOMA METASTASES ; NATURAL-HISTORY ; RADIOFREQUENCY ABLATION ; PATIENT SELECTION ; SURVIVAL ANALYSIS ; PLUS IRINOTECAN
英文摘要:

Aims: To review the latest strategies and controversies in the surgical treatment of liver metastases of colorectal cancer systemically and comprehensively.

Methods: A medline based literature search on relevant topics was performed in PubMed for key articles concerning the novel strategies and controversies in the management of liver metastases of colorectal cancer. Some information was obtained from ′Proc Am Soc Clin Oncol′ published recently. The findings and discussions were related to our own experiences.

Results: Although for well-indicated patients, a consensus has been reached that hepatic resection is the only management that could provide the patients curability, there still exist many controversies, such as the prognostic evaluation, contraindications to hepatic resection, treatment for synchronous liver metastases, the place of laparoscopic surgery, etc. Meanwhile, various strategies to improve the respectabilities are available, including neoadjuvant chemotherapy, portal vein embolization, two stage hepatectomy, and some locally ablative approaches. The current condition is difficult and sometimes confusing for a relevant surgeon when designing treatment protocols for more complex diseases.

Conclusion: As the advancing of the management of liver metastases of colorectal cancer, more patients will become candidates for and benefit from potentially curative surgical resections. Optimal effect could only be achieved when used in a manner tailored to the individual patient (C) 2006 Elsevier Ltd. All rights reserved.

语种: 英语
WOS记录号: WOS:000238638300001
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/53770
Appears in Collections:北京大学临床肿瘤学院_期刊论文

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作者单位: Peking Univ, Sch Oncol, Beijing Canc Hosp, Beijing 100036, Peoples R China

Recommended Citation:
Hao, CY,Ji, JF. Surgical treatment of liver metastases of colorectal cancer: Strategies and controversies in 2006[J]. EJSO,2006,32(5):473-483.
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