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学科主题: 临床医学
题名:
Feasibility of US-CT image fusion to identify the sources of abnormal vascularization in posterior sacroiliac joints of ankylosing spondylitis patients
作者: Hu, Zhenlong1,2; Zhu, Jiaan1,3; Liu, Fang1,2; Wang, Niansong4; Xue, Qin4
刊名: SCIENTIFIC REPORTS
发表日期: 2015-12-16
DOI: 10.1038/srep18356
卷: 5
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Multidisciplinary Sciences
研究领域[WOS]: Science & Technology - Other Topics
关键词[WOS]: COLOR DOPPLER ULTRASONOGRAPHY ; MUSCULOSKELETAL ULTRASOUND ; HEPATOCELLULAR-CARCINOMA ; RHEUMATOLOGY ; DIAGNOSIS ; ANATOMY ; DISEASE
英文摘要:

Ultrasound (US) can be used to evaluate the inflammatory activity of the sacroiliac joints (SIJs) in ankylosing spondylitis (AS) patients, but to precisely locate the abnormal vascularization observed on color Doppler US (CDUS) was difficult. To address this issue, we performed US and computed tomography (CT) fusion imaging of SIJs with 84 inpatients and 30 controls, and then assessed the sources of abnormal vascularization in the posterior SIJs of AS patients based on the fused images. Several possible factors impacting the fusion process were considered including the lesion classes of SIJ, the skinfold thickness of the sacral region and the cross-sectional levels of the first, second and third posterior sacral foramina. Our data showed high image fusion success rates at the 3 levels in the AS group (97.0%, 87.5% and 79.8%, respectively) and the control group (96.7%, 86.7%, and 86.7%, respectively). The skinfold thickness was identified as the main factor affecting the success rates. The successfully fused images revealed significant differences in the distribution of abnormal vascularization between 3 levels, as detected via CDUS (P = 0.011), which suggested that inflammation occurred in distinct tissues at different levels of the SIJ (intraligamentous inflammation in Regions 1 and 2; intracapsular inflammation in Region 3).

语种: 英语
所属项目编号: 81171353
项目资助者: National Natural Science Foundation of China
WOS记录号: WOS:000366483200001
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/53774
Appears in Collections:北京大学第二临床医学院_超声诊断科_期刊论文

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作者单位: 1.Shanghai Inst Ultrasound Med, Shanghai 200233, Peoples R China
2.Shanghai Jiao Tong Univ, Affiliated Peoples Hosp 6, Dept Ultrasound, Shanghai 200233, Peoples R China
3.Peking Univ, Peoples Hosp, Dept Ultrasound, Beijing 100044, Peoples R China
4.Shanghai Jiao Tong Univ, Affiliated Peoples Hosp 6, Dept Rheumatol, Shanghai 200233, Peoples R China

Recommended Citation:
Hu, Zhenlong,Zhu, Jiaan,Liu, Fang,et al. Feasibility of US-CT image fusion to identify the sources of abnormal vascularization in posterior sacroiliac joints of ankylosing spondylitis patients[J]. SCIENTIFIC REPORTS,2015,5.
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