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学科主题: 临床医学
题名:
The safety of long-term cryopreservation on slow-frozen early cleavage human embryos
作者: Liu, Qinli1,2,3; Lian, Ying1,2,3; Huang, Jin1,2,3; Ren, Xiulian1,2,3; Li, Ming1,2,3; Lin, Shengli1,2,3; Liu, Ping1,2,3; Qiao, Jie1,2,3
关键词: Embryo cryopreservation ; Cleavage stage ; Survival ; Singleton birth weight ; Live birth rate
刊名: JOURNAL OF ASSISTED REPRODUCTION AND GENETICS
发表日期: 2014-04-01
DOI: 10.1007/s10815-014-0197-0
卷: 31, 期:4, 页:471-475
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Genetics & Heredity ; Obstetrics & Gynecology ; Reproductive Biology
研究领域[WOS]: Genetics & Heredity ; Obstetrics & Gynecology ; Reproductive Biology
关键词[WOS]: 8-CELL MOUSE EMBRYOS ; SURVIVAL ; STORAGE ; SUCCESS
英文摘要:

To evaluate the impact of cryopreservation storage time on cleavage-stage embryo survival rate, pregnancy rate, implantation rate, singleton birth weight, and live birth rate.

This study was a retrospective analysis, including 867 thaw cycles and 3,367 embryos. Women who underwent IVF-FET cycles between 2005 and 2012 were analyzed. The patients were divided into four groups, as follows: group 1 (12-23 months); group 2 (24-35 months); group 3 (36-48 months); and group 4 (a parts per thousand yen48 months).

The storage time did not have a significant effect on survival, damage rate of the blastomeres, implantation rate, pregnancy rate, singleton birth weight, and live birth rate for embryos frozen at cleavage stages.

Storage time did not influence the survival and pregnancy outcomes of slow-frozen early cleavage human embryos. The developmental potential of cryopreserved human embryos with different storage times does not appear to have a negative influence on further development.

语种: 英语
所属项目编号: 30900512 ; 810705340/H0426
项目资助者: Natural Sciences Foundation of China
WOS记录号: WOS:000333703100012
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/53786
Appears in Collections:北京大学第三临床医学院_生殖医学中心_期刊论文

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作者单位: 1.Minist Educ, Key Lab Assisted Reprod, Beijing, Peoples R China
2.Peking Univ Third Hosp, Dept Obstet & Gynecol, Reprod Med Ctr, Beijing, Peoples R China
3.Beijing Key Lab Reprod Endocrinol & Assisted Repr, Beijing, Peoples R China

Recommended Citation:
Liu, Qinli,Lian, Ying,Huang, Jin,et al. The safety of long-term cryopreservation on slow-frozen early cleavage human embryos[J]. JOURNAL OF ASSISTED REPRODUCTION AND GENETICS,2014,31(4):471-475.
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