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Quality evaluation of medicinally-used Codonopsis species and Codonopsis Radix based on the contents of pyrrolidine alkaloids, phenylpropanoid and polyacetylenes
He, Jing-Yu1; Zhu, Shu1; Goda, Yukihiro2; Cai, Shao-Qing3; Komatsu, Katsuko1
关键词Codonopsis Quantitative Analysis Alkaloids Phenylpropanoid Polyacetylenes
刊名JOURNAL OF NATURAL MEDICINES
2014-04-01
DOI10.1007/s11418-013-0801-0
68期:2页:326-339
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Chemistry, Medicinal ; Pharmacology & Pharmacy
研究领域[WOS]Pharmacology & Pharmacy
关键词[WOS]LOBELIA-INFLATA ; TANGSHEN OLIV ; DERIVATIVES ; LOBETYOLIN ; ROOTS
英文摘要

A comparative study of 56 specimens of three medicinally-used Codonopsis taxa collected from China and 54 commercial samples of Codonopsis Radix available in Chinese, Japanese and Korean markets was carried out by quantitative analysis of seven major components: codonopyrrolidium B (1), codonopyrrolidium A (2), tangshenoside I (3), cordifolioidyne B (4), lobetyolinin (5), lobetyolin (6) and lobetyol (7). The quantitative results, based on a well-established HPLC-DAD method, indicated that the contents of these seven compounds varied considerably among the samples, not only inter-species but also intra-species. C. pilosula and C. pilosula var. modesta showed similar chemical compositions, while C. tangshen differed considerably from these two in chemical composition. The results of principal component analysis (PCA) indicated that two main groups were classified; one group mainly included C. pilosula, C. pilosula var. modesta and the commercial samples derived from these two taxa, while the other group was composed of C. tangshen and its derived commercial samples. Compound 1 was the main component in the roots of C. pilosula and C. pilosula var. modesta, while 3 and 2 had relatively high contents in the roots of C. tangshen. Therefore, 3, 2 and 1 could be chemical markers to differentiate C. tangshen from C. pilosula and C. pilosula var. modesta.

语种英语
WOS记录号WOS:000332826900009
项目编号21406004 ; 24406005 ; KHB1008
资助机构JSPS ; Japan Health Sciences Foundation ; MEXT, Japan
引用统计
被引频次:12[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/53810
专题北京大学药学院
北京大学药学院_天然药物学系
作者单位1.Toyama Univ, Inst Nat Med, Div Pharmacognosy, Dept Med Resources, Toyama 9300194, Japan
2.Natl Inst Hlth Sci, Div Pharmacognosy Phytochem & Narcot, Setagaya Ku, Tokyo 1588501, Japan
3.Peking Univ, Sch Pharmaceut Sci, Beijing 100191, Peoples R China
推荐引用方式
GB/T 7714
He, Jing-Yu,Zhu, Shu,Goda, Yukihiro,et al. Quality evaluation of medicinally-used Codonopsis species and Codonopsis Radix based on the contents of pyrrolidine alkaloids, phenylpropanoid and polyacetylenes[J]. JOURNAL OF NATURAL MEDICINES,2014,68(2):326-339.
APA He, Jing-Yu,Zhu, Shu,Goda, Yukihiro,Cai, Shao-Qing,&Komatsu, Katsuko.(2014).Quality evaluation of medicinally-used Codonopsis species and Codonopsis Radix based on the contents of pyrrolidine alkaloids, phenylpropanoid and polyacetylenes.JOURNAL OF NATURAL MEDICINES,68(2),326-339.
MLA He, Jing-Yu,et al."Quality evaluation of medicinally-used Codonopsis species and Codonopsis Radix based on the contents of pyrrolidine alkaloids, phenylpropanoid and polyacetylenes".JOURNAL OF NATURAL MEDICINES 68.2(2014):326-339.
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