北京大学医学部机构知识库
Advanced  
IR@PKUHSC  > 北京大学第三临床医学院  > 肾内科  > 期刊论文
学科主题: 临床医学
题名:
Pulse wave velocity is associated with metabolic syndrome components in CAPD patients
作者: Zhe, Xing-wei1; Zeng, Jing1; Tian, Xin-kui1; Chen, Wei1; Gu, Yue1; Cheng, Li-tao1; Chen, Hui-min1; Axelsson, Jonas2; Lindholm, Bengt2; Wang, Tao1
关键词: arterial stiffness ; chronic kidney disease ; hypertension ; dyslipidemia ; cardiovascular disease
刊名: AMERICAN JOURNAL OF NEPHROLOGY
发表日期: 2008
DOI: 10.1159/000117813
卷: 28, 期:4, 页:641-646
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Urology & Nephrology
研究领域[WOS]: Urology & Nephrology
关键词[WOS]: PERITONEAL-DIALYSIS PATIENTS ; CHRONIC KIDNEY-DISEASE ; CORONARY-ARTERY-DISEASE ; STAGE RENAL-DISEASE ; AORTIC STIFFNESS ; CARDIOVASCULAR MORTALITY ; ALL-CAUSE ; ESSENTIAL-HYPERTENSION ; INDEPENDENT PREDICTOR ; VALVE CALCIFICATION
英文摘要:

Background: Overall, the proportion of deaths due to cardiovascular disease (CVD) reached 40-50% in dialysis patients. Pulse wave velocity (PWV) reflects arterial stiffness and may provide an integrated index of vascular status and CVD risk. Individual components of the metabolic syndrome (MetS) are well-established cardiovascular risk factors. Thus we conducted a cross-sectional study in continuous ambulatory peritoneal dialysis (CAPD) patients to explore the association of MetS components with PWV. Methods: Prevalent CAPD patients (n = 148, 63 M/85 F) were categorized according to the number of traits of the MetS into one of three groups (No MetS, Risk of MetS, MetS). Due to the effect of peritoneal dialysis (PD), waist circumference was not assessed. Aortic stiffness was assessed by carotid-femoral PWV (C-F PWV). Results: Patients′ MetS trait numbers were positively associated with C-F PWV (r = 0.301, p < 0.01), pulse pressure (r = 0.256, p < 0.01), systolic blood pressure (r = 0.233, p < 0.01), and serum albumin (r = 0.205, p < 0.05). In a multivariate regression analysis, PWV was independently determined by age (p < 0.01) and MetS score (p = 0.01). Adjusted R 2 of the model was 0.24. Conclusion: MetS traits were closely associated with an increased C-F PWV, even after adjustment for confounders. This suggests that commonly recognized MetS criteria are useful also when predicting CVD in CAPD patients. Copyright (C) 2008 S. Karger AG, Basel.

语种: 英语
WOS记录号: WOS:000255896200013
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/53927
Appears in Collections:北京大学第三临床医学院_肾内科_期刊论文

Files in This Item:

There are no files associated with this item.


作者单位: 1.Peking Univ, Div Nephrol, Hosp 3, Beijing 100083, Peoples R China
2.Karolinska Inst, Div Renal Med & Baxter Novum, Dept Clin Sci Intervent & Technol, Stockholm, Sweden

Recommended Citation:
Zhe, Xing-wei,Zeng, Jing,Tian, Xin-kui,et al. Pulse wave velocity is associated with metabolic syndrome components in CAPD patients[J]. AMERICAN JOURNAL OF NEPHROLOGY,2008,28(4):641-646.
Service
Recommend this item
Sava as my favorate item
Show this item's statistics
Export Endnote File
Google Scholar
Similar articles in Google Scholar
[Zhe, Xing-wei]'s Articles
[Zeng, Jing]'s Articles
[Tian, Xin-kui]'s Articles
CSDL cross search
Similar articles in CSDL Cross Search
[Zhe, Xing-wei]‘s Articles
[Zeng, Jing]‘s Articles
[Tian, Xin-kui]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Copyright © 2007-2017  北京大学医学部 - Feedback
Powered by CSpace