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学科主题临床医学
Risk factors of diabetic retinopathy in type 2 diabetic patients
Cai, XL; Wang, F; Ji, LN
关键词Diabetic Retinopathy Type 2 Diabetes Risk Factors
刊名CHINESE MEDICAL JOURNAL
2006-05-20
119期:10页:822-826
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Medicine, General & Internal
研究领域[WOS]General & Internal Medicine
关键词[WOS]HARD EXUDATE ; PROGRESSION ; COMPLICATIONS ; MELLITUS
英文摘要

Background Advances in treatment have greatly reduced the risk of blindness from this disease, but because diabetes is so common, diabetic retinopathy remains an important problem. The purpose of this study is to investigate the risk factors of diabetic retinopathy (DR) in Chinese type 2 diabetic patients.

Methods Totally 746 type 2 diabetic patients were selected for biochemical and clinical characteristics test and examined by the retina-camera for diabetic retinopathy and the average age was 55.9 years old.

Results A total of 526 patients was classified as non-DR, 159 patients as non-proliferative-DR and 61 patients as proliferative-DR. Duration of diabetes [(66.09 +/- 72.51) months vs (143.71 +/- 93.27) months vs (174.30 +/- 81.91) months, P=0.00], systolic blood pressure [(131.95 +/- 47.20) mmHg vs (138.71 +/- 21.36) mmHg vs (147.58 +/- 24.10) mmHg, P=0.01], urine albumin [(32.79 +/- 122.29) mg/L vs (190.96 +/- 455.65) mg/L vs (362.00 +/- 552.51) mg/L, P=0.001, glycated hemoglobin (HbAlc) [(8.68 +/- 2.26)% vs (9.42 +/- 1.84)% vs (9.42 +/- 1.96)%, P=0.04], C-reactive protein (CRP) [(3.19 +/- 7.37) mg/L vs (6.36 +/- 23.59) mg/L vs (3.02 +/- 4.34) mg/L, P=0.03], high-density lipoprotein cholesterol (HDL-C) [(1.23 +/- 0.37) mmol/L vs (1.33 +/- 0.35) mmol/L vs (1.24 +/- 0.33) mmol/L, P=0.01], uric acid (UA) [(288.51 +/- 90.85) mmol/L vs (300.29 +/- 101.98) mmol/L vs (337.57 +/- 115.09) mmol/L, P=0.00], creatinine (CREA) [(84.22 +/- 16.31) mu mol/L vs (89.35 +/- 27.45) pmol/L vs (103.28 +/- 48.64) pmol/L, P=0.00], blood urine nitrogen (BUN) [(5.62 +/- 1.62) mmol/L vs (6.55 +/- 2.74) mmol/L vs (8.11 +/- 3.60) mmol/L, P=0.00] were statistically different among the three groups. Logistic regression analysis showed that diabetic duration and urine albumin were two independent risk factors of DR (the OR values were 1.010 and 1.003 respectively).

Conclusions Diabetic duration and urine albumin are two independent risk factors of diabetic retinopathy in elderly type 2 diabetic patients.

语种英语
WOS记录号WOS:000237907200005
引用统计
被引频次:27[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/53945
专题北京大学第二临床医学院
作者单位Peking Univ, Peoples Hosp, Dept Endocrinol & Metab, Beijing 100044, Peoples R China
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GB/T 7714
Cai, XL,Wang, F,Ji, LN. Risk factors of diabetic retinopathy in type 2 diabetic patients[J]. CHINESE MEDICAL JOURNAL,2006,119(10):822-826.
APA Cai, XL,Wang, F,&Ji, LN.(2006).Risk factors of diabetic retinopathy in type 2 diabetic patients.CHINESE MEDICAL JOURNAL,119(10),822-826.
MLA Cai, XL,et al."Risk factors of diabetic retinopathy in type 2 diabetic patients".CHINESE MEDICAL JOURNAL 119.10(2006):822-826.
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