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学科主题: 临床医学
题名:
The increased range of cervical flexed motion detected by radiographs in Hirayama disease
作者: Xu, Xiaojuan1; Han, Hongbin1; Gao, Hui1; Hou, Chao1; Fan, Dongsheng2; Fu, Yu2; Sun, Yu3
关键词: Hirayama disease ; Range of cervical flexed motion ; Radiographs ; Magnetic resonance imaging
刊名: EUROPEAN JOURNAL OF RADIOLOGY
发表日期: 2011-04-01
DOI: 10.1016/j.ejrad.2010.08.012
卷: 78, 期:1, 页:82-86
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Radiology, Nuclear Medicine & Medical Imaging
研究领域[WOS]: Radiology, Nuclear Medicine & Medical Imaging
关键词[WOS]: JUVENILE MUSCULAR-ATROPHY ; DISTAL UPPER EXTREMITY ; FLEXION MYELOPATHY ; SPINAL-CORD ; EXTENSION ; VALIDITY
英文摘要:

Purpose: Cervical flexion movement is supposed to play an important role in the pathogenesis of Hirayama disease. But there is no report on the range of cervical flexed motion in this disease. The purpose of current study was to compare the range of cervical flexed motion in patients with Hirayama disease with the one in healthy controls using conventional lateral flexion radiographs of the cervical spine, and to investigate the diagnostic value of radiographs for Hirayama disease.

Materials and methods: This prospective study was approved by a local institutional review board and written informed consent was obtained. From August 2007 to March 2009, conventional flexion cervical radiographs and flexion cervical MRI were performed on 31 Hirayama disease patients (all men, age range, 16-24 years, mean age, 19.52 +/- 2.29 years) and 40 control subjects (all men, age range, 16-25 years, mean age, 23.10 +/- 2.20 years). The segmental and overall range of cervical flexed motion was quantitatively measured. Receiver operating characteristic curve was calculated and the diagnostic accuracy was qualified by using the area under the curve Az.

Results: Both the segmental and overall range of cervical flexed motion of patients determined by flexion cervical radiographs was greater than that of controls. The Az value was 0.90, indicating a moderate to good ability of conventional flexion radiographs in the diagnosis of Hirayama disease.

Conclusion: Hirayama disease patients have an increased flexed motion range of cervical spine which would contribute to the pathophysiological change and determine its treatment. Conventional flexion radiographs might be suitable to be used as first line radiographic examination, followed by MRI in cases of suspected Hirayama disease. (C) 2010 Elsevier Ireland Ltd. All rights reserved.

语种: 英语
所属项目编号: NCET-05-0019
项目资助者: Project of New Century Excellent Talents in University of China
WOS记录号: WOS:000289558000012
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/53964
Appears in Collections:北京大学第三临床医学院_放射科_期刊论文

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作者单位: 1.Peking Univ, Dept Radiol, Hosp 3, Beijing 100191, Peoples R China
2.Peking Univ, Dept Neurol, Hosp 3, Beijing 100191, Peoples R China
3.Peking Univ, Dept Orthoped, Hosp 3, Beijing 100191, Peoples R China

Recommended Citation:
Xu, Xiaojuan,Han, Hongbin,Gao, Hui,et al. The increased range of cervical flexed motion detected by radiographs in Hirayama disease[J]. EUROPEAN JOURNAL OF RADIOLOGY,2011,78(1):82-86.
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