学科主题临床医学
Efficacy of physical examination, ultrasound, and ultrasound combined with fine-needle aspiration for axilla staging of primary breast cancer
Feng, Yu1; Huang, Rui1; He, Yingjian1; Lu, Aiping2; Fan, Zhaoqing1; Fan, Tie1; Qi, Meng1; Wang, Xinguang1; Cao, Wei1; Wang, Xing1; Xie, Yuntao1; Wang, Tianfeng1; Li, Jinfeng1; Ouyang, Tao1
关键词Ultrasonography Fine-needle Axillary Biopsy Axillary Staging Sentinel Lymph Node Biopsy
刊名BREAST CANCER RESEARCH AND TREATMENT
2015-02-01
DOI10.1007/s10549-015-3280-z
149期:3页:761-765
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Oncology
研究领域[WOS]Oncology
关键词[WOS]LYMPH-NODE BIOPSY ; SENTINEL NODE ; PREOPERATIVE ULTRASONOGRAPHY ; METASTASES ; MAMMOGRAPHY ; CARCINOMA ; DIAGNOSIS ; ACCURACY ; CYTOLOGY ; MANAGEMENT
英文摘要

The aim of this study was to compare the efficacy of physical examination (PE), ultrasound (US), and US combined with fine-needle cytology (US-FNAC) in evaluation of node status before sentinel lymph node biopsy (SLNB) for breast cancer patients. We performed a retrospective study of 3,781 breast cancer patients and calculated the sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and accuracy for PE, US, and US-FNAC, respectively. A total of 3,175 cases were documented as cN(0) and 606 as cN(1). Abnormal axillary nodes under US were detected in 1,152 cases, among which 821 were proven to have positive nodes by FNAC. The positive FNAC results enabled 11.7 % of cN(0) patients (373/3,175) to avoid unnecessary SLNB. All 331 cases with abnormal US but negative FNAC results, and the 2,629 cases with normal US underwent SLNB procedure for nodal staging, and metastatic nodes were identified in 745 patients. The sensitivity of PE was 32.2 %, with a specificity of 95.5 %, a PPV of 83.5 %, a NPV of 65 %, and an accuracy of 69.3 %. The sensitivity, specificity, PPV, NPV, and accuracy of axillary US alone were 58.6, 89.4, 79.6, 75.3, and 76.7 %, respectively. Combining axillary US with FNAC resulted in sensitivity, specificity, PPV, NPV, and accuracy of 52.4, 100, 100, 74.8, and 80.3 %, respectively. Our study demonstrated that US-FNAC is a feasible and effective triage during axillary staging for newly diagnosed breast cancer patients.

语种英语
WOS记录号WOS:000349761200018
引用统计
被引频次:10[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/53968
专题北京大学临床肿瘤学院_乳腺癌预防治疗中心
北京大学临床肿瘤学院_病理科
作者单位1.Peking Univ Canc Hosp & Inst, Canc Hosp & Inst, Minist Educ, Key Lab Carcinogenesis & Translat Res, Beijing 100142, Peoples R China
2.Peking Univ Canc Hosp & Inst, Minist Educ, Dept Pathol, Key Lab Carcinogenesis & Translat Res, Beijing 100142, Peoples R China
推荐引用方式
GB/T 7714
Feng, Yu,Huang, Rui,He, Yingjian,et al. Efficacy of physical examination, ultrasound, and ultrasound combined with fine-needle aspiration for axilla staging of primary breast cancer[J]. BREAST CANCER RESEARCH AND TREATMENT,2015,149(3):761-765.
APA Feng, Yu.,Huang, Rui.,He, Yingjian.,Lu, Aiping.,Fan, Zhaoqing.,...&Ouyang, Tao.(2015).Efficacy of physical examination, ultrasound, and ultrasound combined with fine-needle aspiration for axilla staging of primary breast cancer.BREAST CANCER RESEARCH AND TREATMENT,149(3),761-765.
MLA Feng, Yu,et al."Efficacy of physical examination, ultrasound, and ultrasound combined with fine-needle aspiration for axilla staging of primary breast cancer".BREAST CANCER RESEARCH AND TREATMENT 149.3(2015):761-765.
条目包含的文件
条目无相关文件。
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Feng, Yu]的文章
[Huang, Rui]的文章
[He, Yingjian]的文章
百度学术
百度学术中相似的文章
[Feng, Yu]的文章
[Huang, Rui]的文章
[He, Yingjian]的文章
必应学术
必应学术中相似的文章
[Feng, Yu]的文章
[Huang, Rui]的文章
[He, Yingjian]的文章
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。