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学科主题: 临床医学
题名:
Catestatin is useful in detecting patients with stage B heart failure
作者: Zhu, Dan; Wang, Fangfang; Yu, Haiyi; Mi, Lin; Gao, Wei1
关键词: Catestatin ; B-type brain natriuretic peptide (BNP) ; heart failure ; biomarkers
刊名: BIOMARKERS
发表日期: 2011-12-01
DOI: 10.3109/1354750X.2011.629058
卷: 16, 期:8, 页:691-697
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Biotechnology & Applied Microbiology ; Toxicology
研究领域[WOS]: Biotechnology & Applied Microbiology ; Toxicology
关键词[WOS]: INHIBITORY PEPTIDE CATESTATIN ; VENTRICULAR SYSTOLIC DYSFUNCTION ; BRAIN NATRIURETIC PEPTIDE ; CATECHOLAMINE RELEASE ; CHROMOGRANIN-A ; ARTERIAL-HYPERTENSION ; MYOCARDIAL-INFARCTION ; DIAGNOSTIC-ACCURACY ; TERMINAL PROBNP ; TASK-FORCE
英文摘要:

Screening patients with stage B heart failure(HF) may be one strategy for reducing human morbidity. To describe catestatin levels in different stages of HF and evaluate the diagnostic utility of catestatin for detecting stage B HF, we included 300 patients. Catestatin, BNP testing and echocardiogram were performed. Our studies showed catestatin decreased gradually from stage A to C. There was significant difference between stage A and B. Cutoff value for detecting stage B HF was 19.73 ng/ml for catestatin with 90% sensitivity and 50.9% specificity. These results may have implications in the new method to detect patients with stage B HF.

语种: 英语
所属项目编号: 2007CB512107/2007CB 512108 ; 80489-01
项目资助者: National Ministry of Science and Technology ; Peking University Third Hospital
WOS记录号: WOS:000297225000010
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/53989
Appears in Collections:北京大学第三临床医学院_心血管内科_期刊论文

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作者单位: 1.Peking Univ, Hosp 3, Dept Cardiol, Beijing 100191, Peoples R China
2.Minist Educ, Key Lab Cardiovasc Mol Biol & Regulatory Peptides, Minist Hlth, Beijing, Peoples R China
3.Minist Educ, Key Lab Mol Cardiovasc Sci, Beijing, Peoples R China

Recommended Citation:
Zhu, Dan,Wang, Fangfang,Yu, Haiyi,et al. Catestatin is useful in detecting patients with stage B heart failure[J]. BIOMARKERS,2011,16(8):691-697.
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